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About This Item
經驗公式(希爾表示法):
C13H9NO4
CAS號碼:
分子量::
243.21
Beilstein:
5749492
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
暫時無法取得訂價和供貨情況
等級
certified reference material
agency
BCR®
製造商/商標名
JRC
技術
HPLC: suitable
gas chromatography (GC): suitable
形式
neat
儲存溫度
2-8°C
SMILES 字串
COc1ccc2c(ccc3oc(cc23)[N+]([O-])=O)c1
InChI
1S/C13H9NO4/c1-17-9-3-4-10-8(6-9)2-5-12-11(10)7-13(18-12)14(15)16/h2-7H,1H3
InChI 密鑰
BRRIJZQYTOFDAF-UHFFFAOYSA-N
分析報告
For more information please see:
BCR312
BCR312
法律資訊
BCR is a registered trademark of European Commission
訊號詞
Warning
危險聲明
危險分類
Muta. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
P Quillardet et al.
Mutation research, 422(2), 237-245 (1998-12-05)
DNA adducts that block replication, induced in vivo by the 5-nitrofuran derivative R7000 (7-methoxy-2-nitronaphtho[2, 1-b]-furan) were mapped, at nucleotide resolution, in a region of the lacI gene of Escherichia coli, using a reiterative primer extension assay [D. Chandrasekhar, B. Van
E Touati et al.
Carcinogenesis, 17(12), 2543-2550 (1996-12-01)
The mutagenic specificity of 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), a very potent genotoxic 2-nitrofuran, was investigated in the lacI gene of E.coli. To analyze the influence of SOS-mutagenesis on R7000-induced mutations, 86 and 84 LacI- mutants were respectively isolated from umuC+ and umuC
E Touati et al.
Mutagenesis, 4(4), 254-258 (1989-07-01)
The effects on DNA, in bacteria, of 7-methoxy-2-nitro-naphtho[2,1-b]furan (R7000), a very potent genotoxic product from the 2-nitronaphthofuran series, were investigated with two different approaches: (i) measurement of the binding of the radiolabelled mutagen to DNA and (ii) detection by the
P Quillardet et al.
Mutation research, 204(2), 141-147 (1988-02-01)
We measured the genotoxic activities in two bacterial tests, the Salmonella/histidine assay (a reverse mutation assay) and the SOS chromotest (an assay for SOS induction in E. coli), of three 2-nitroanthrafurans: 2-nitroanthra[1,2-b]furan (R-7688), the isomeric compound 2-nitroanthra[2,1-b]furan (R-7686) and its
E Touati et al.
Mutagenesis, 8(2), 149-154 (1993-03-01)
The characterization of target nucleotides involved in the binding to DNA of 7-methoxy-2-nitro-naphtho[2,1-b]furan (R7000), a very potent genotoxic nitrofuran derivative, was investigated. Since R7000 undergoes metabolic activation prior to interacting with DNA, plasmids containing AT-rich and GC-rich sequences were devised
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