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B1116000

生物素

European Pharmacopoeia (EP) Reference Standard

同義詞:

D-生物素, Bios II, 维生素B7, 维生素H, 辅酶 R

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About This Item

經驗公式(希爾表示法):
C10H16N2O3S
CAS號碼:
分子量::
244.31
Beilstein:
86838
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

EP

API 家族

biotin

形狀

solid

製造商/商標名

EDQM

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

231-233 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI 密鑰

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Biotin is a water-soluble vitamin B, which is involved in the synthesis of fatty acids and in gluconeogenesis. It is found in plants and animals. Biotin deficiency causes retardation in growth, alopecia and neurological impairment in humans and animals.

應用

Biotin may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Biotin
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 16(8), 5631-5632 (2018)
Liquid chromatographic determination of biotin in multivitamin-multimineral tablets.
Ekpe AE and Hazen C
Journal of Pharmaceutical and Biomedical Analysis, 16(8), 1311-1315 (1998)
Agar plate method using Lactobacillus plantarum for biotin determination in serum and urine
FUKUI T, et al.
J. Nutr. Sci. Vitaminol., 40(5), 491-498 (1994)
Magnetic resonance imaging assays for dimethyl sulfoxide effect on cancer vasculature
Cyran CC, et al.
Investigative Radiology, 43(5), 298-298 (2008)
Factitious Graves disease due to biotin immunoassay interference-a case and review of the literature
Elston MS, et al.
The Journal of clinical endocrinology and metabolism, 101(9), 3251-3255 (2016)

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