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重要文件

X114

Sigma-Aldrich

Triton X-114

laboratory grade

同義詞:

(1,1,3,3-四甲基丁基)苯基-聚乙二醇, 聚乙二醇叔辛基苯基醚

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About This Item

線性公式:
(C2H4O)n C14H22O, n = 7 or 8
CAS號碼:
Beilstein:
2315025
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.21
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等級

laboratory grade

品質等級

描述

non-ionic

分子量

average mol wt 537

成份

t-Oct-C6H4-(OCH2CH2)xOH, x = 7-8

折射率

n20/D 1.488 (lit.)

CMC

0.2 mM (20-25°C)

轉變溫度

pour point ~−9 °C
cloud point 23 °C

密度

1.058 g/mL at 25 °C (lit.)

HLB

12.4

SMILES 字串

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI 密鑰

HNLXNOZHXNSSPN-UHFFFAOYSA-N

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一般說明

Triton X-114是一种非离子洗涤剂。该洗涤剂能够溶解膜,具有反相分离特性,可用于固有膜蛋白分离。[1]Triton X-114溶液在0℃为均质状态,但20℃以上条件会发生相分离形成水相和洗涤剂相。[2]蛋白质在Triton X-114溶液中的相分离已经过研究。[1]辛基苯酚乙氧基化物和阴离子、阳离子和其他非离子表面活性剂兼容,在大多数酸性 &碱性溶液中化学性质稳定。

應用

Triton X-114已用于:
  • 通过相分离技术,从蛋白质溶液中去除内毒素[3]
  • 从内毒素中提取和纯化DNA[4]
  • 从细菌细胞壁二相提取脂蛋白[5][6]
  • 一种低浊点(23 °C)的非离子除垢剂,能够溶解蛋白质,从两性蛋白相分离亲水蛋白

法律資訊

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

483.8 °F - closed cup

閃點(°C)

251 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Nozomu Takahashi et al.
FEBS open bio, 7(9), 1338-1349 (2017-09-15)
Neuroglobin (Ngb) is a heme protein expressed in the vertebrate brain. We previously engineered a chimeric Ngb protein, in which module M1 of human Ngb is replaced by that of zebrafish Ngb, and showed that the chimeric ZHHH Ngb has
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Golenbock D T, et al.
Cellular Immunology, 258(1), 29-37 (2009)
Huanhuan Li et al.
Life sciences, 231, 116548-116548 (2019-06-11)
Multidrug resistance is a major obstacle in chemotherapy, which is mainly caused by the overexpression of ATP-binding cassette (ABC) transporters. Breast cancer resistance protein (BCRP) is one of the ABC transporters and is strongly associated with multidrug resistance. Results of
Mechanism and function of a newly identified CpG DNA motif in human primary B cells.
Hartmann G and Krieg A M
Journal of Immunology, 164(2), 944-953 (2000)
G Gabarrini et al.
Journal of dental research, 97(5), 556-562 (2018-01-05)
Porphyromonas gingivalis is one of the major oral pathogens implicated in the widespread inflammatory disorder periodontitis. Moreover, in recent years, P. gingivalis has been associated with the autoimmune disease rheumatoid arthritis. The peptidylarginine deiminase enzyme of P. gingivalis (PPAD) is

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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