74023

trans-2-Dodecenoyl-L-carnitine

analytical standard

• 同義詞: (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-dodecen-1-yl]oxy]-1-propanaminium inner salt, C12:1-Carnitine
• 經驗公式（希爾表示法）: C₁₉H₃₅NO₄
• CAS號碼: 1631992-06-7
• 分子量：: 341.49
• 分類程式碼代碼: 12352200
• NACRES: NB.21

屬性

• 等級: analytical standard
• 品質等級: 100
• 化驗: ≥93.0% (HPLC)
• 光學活性: [α]/D -15±2°, c = 0.1 in methanol
• 儲存期限: limited shelf life, expiry date on the label
• 應用: clinical testing
• 形式: neat
• 儲存溫度: −20°C
• SMILES 字串: [O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O

描述

一般說明

trans-2-Dodecenoyl-L-carnitine belongs to the class of medium-chain acylcarnitines.[1] Acyl-L-carnitines are mostly produced from L-carnitine, which plays an important role in fatty acid metabolic pathways. It acts as a carrier of long-chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

trans-2-Dodecenoyl-L-carnitine, belongs to the class of acylcarnitines. It serves as a specific diagnostic metabolite biomarker, which increases in very-long-chain acyl CoA dehydrogenase (VLCAD) deficiency, determined in biological samples.[2][3]

應用

trans-2-Dodecenoyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological fluids of horses with atypical myopathy using gas chromatography coupled to mass spectrometry.[4] It may also be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS).[5]

trans-2-Dodecenoyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples of horses with atypical myopathy using gas chromatography-mass spectrometry (GC−MS).[4] It may also be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS).[5]

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安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable