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Merck
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重要文件

46738

Supelco

大观霉素 二盐酸盐 五水合物

VETRANAL®, analytical standard

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About This Item

經驗公式(希爾表示法):
C14H24N2O7 · 2HCl · 5H2O
CAS號碼:
分子量::
495.35
Beilstein:
5684150
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

溶解度

H2O: soluble at 

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

應用

clinical testing

形式

neat

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2

InChI

1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1

InChI 密鑰

DCHJOVNPPSBWHK-UXXUFHFZSA-N

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一般說明

Chemical structure: aminoglycoside

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Spectinomycin dihydrochloride pentahydrate may be used as a reference standard for the determination of spectinomycin in bovine milk samples by liquid chromatography with electrochemical detection.[1]
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

注意

Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.

準備報告

Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Determination of spectinomycin residues in bovine milk using liquid chromatography with electrochemical detection.
Schermerhorn PG, et al.
Journal of Agricultural and Food Chemistry, 43(8), 2122- 2125 (1995)
Yi-Ywan M Chen et al.
Applied and environmental microbiology, 77(12), 3967-3974 (2011-05-03)
Streptococcus parasanguinis is among the most successful colonizers of the human body. Strain FW213 harbors a 7.0-kb cryptic plasmid, pFW213, with a copy number at 5 to 10 per chromosome. Sequence and functional analyses of pFW213 revealed that the open
Janice Yee Chi Lo et al.
The Journal of antimicrobial chemotherapy, 67(6), 1422-1426 (2012-02-16)
To undertake laboratory and clinical surveillance of gonococcal antimicrobial susceptibility to various therapeutic agents in Hong Kong, so as to monitor for emerging resistance and to inform on appropriate choice of empirical therapy. Trends in susceptibility of gonococci to ceftriaxone
Laurence Meslet-Cladière et al.
Eukaryotic cell, 10(12), 1670-1678 (2011-10-18)
The green alga Chlamydomonas reinhardtii today is a premier model organism for the study of green algae and plants. Yet the efficient engineering of its nuclear genome requires development of new antibiotic resistance markers. We have recoded, based on codon
Z-G Bai et al.
International journal of STD & AIDS, 23(2), 126-132 (2012-03-17)
We conducted a systematic review and meta-analysis of ceftriaxone for treatment of uncomplicated gonorrhoea compared with four other antibiotics. Thirteen randomized controlled trials (RCTs) totalling treatment of 2557 patients with uncomplicated gonorrhoea were included. Statistically significant differences were observed in

文章

LC/LC-MS method identifies 8 aminoglycosides in pork using Discovery® DSC-18 SPE and Ascentis® Express C18 UHPLC, per Chinese standards.

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