D7253

双氢链霉素倍半硫酸酯

Name: 双氢链霉素 倍半硫酸酯
Brand: SIGMA

同義詞:

Didromycin, Dihydrostreptomycin 3/2 sulfate, Dihydrostreptomycin sulfate

Slide 1 of 1

登入檢視組織與合約價格。

選擇尺寸

暫時無法取得訂價和供貨情況

關於此項目

線性公式:

C₂₁H₄₁N₇O₁₂ · 3/2H₂SO₄

CAS 編號:

5490-27-7

分子量：:

730.71

UNSPSC Code:

51102829

NACRES:

NA.85

PubChem Substance ID:

24894093

EC Number:

226-823-7

Beilstein/REAXYS Number:

3894221

MDL number:

MFCD00070252

重要文件

檢視所有文件

跳轉至

技術服務

需要援助？我們經驗豐富的科學家團隊隨時樂意為您提供支援。

讓我們為您提供幫助

InChI key

CZWJCQXZZJHHRH-YZTFXSNBSA-N

InChI

1S/2C21H41N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)CO)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)CO)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N

biological source

microbial

form

powder

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycobacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

200

尋找類似的產品？前往產品比較指南

比較類似項目

查看完整比較

Show Differences

1 of 4

本產品	1203008	D5155	D1954000
Sigma-Aldrich D7253 Dihydrostreptomycin sesquisulfate	USP 1203008 Dihydrostreptomycin sulfate	Sigma-Aldrich D5155 Dihydrostreptomycin sesquisulfate	D1954000 Dihydrostreptomycin sulfate
antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria	antibiotic activity spectrum -	antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria	antibiotic activity spectrum -
mode of action protein synthesis \| interferes	mode of action -	mode of action protein synthesis \| interferes	mode of action -
Quality Level 200	Quality Level -	Quality Level 200	Quality Level -
form powder	form -	form powder	form -
biological source microbial	biological source -	biological source -	biological source -
storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C	storage temp. -

General description

Chemical structure: aminoglycoside

Application

Dihydrostreptomycin sesquisulfate is a derivative of streptomycin used in aminoglycoside uptake studies[1][2]. It has also been used as an electrode for a cochlear amplifier in the hair-cell bundle of lizards[3].

Biochem/physiol Actions

Mode of Action: Dihydrostreptomycin sesquisulfate inhibits protein synthesis at the level of the 30s ribosomal subunit and the 16s rRNA.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361fd

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

存儲類別/等級

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

未看到正確版本？

如果您需要一個特定的版本，您可以透過批號來尋找特定憑證。

搜尋 COA

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

In vitro studies simultaneously examining effect of oxacillin on uptake of radiolabeled streptomycin and on associated bacterial lethality in Staphylococcus aureus.

J M Zenilman et al.

Antimicrobial agents and chemotherapy, 30(6), 877-882 (1986-12-01)

We studied the effects of various concentrations of oxacillin on streptomycin uptake and killing for several strains of Staphylococcus aureus. When streptomycin was present in concentrations below the MIC, addition of oxacillin at concentrations greater than or equal to the

Gentamicin uptake in Staphylococcus aureus possessing plasmid-encoded, aminoglycoside-modifying enzymes.

L J Mandel et al.

Antimicrobial agents and chemotherapy, 26(4), 563-569 (1984-10-01)

[3H]gentamicin uptake and killing were studied in three strains of gentamicin-resistant Staphylococcus aureus possessing plasmid-encoded, gentamicin-modifying enzymes and in three isogenic, enzyme-free, gentamicin-susceptible derivatives. At low (less than or equal to 2.0 micrograms/ml) concentrations of gentamicin, uptake by resistant organisms

In vivo evidence for a cochlear amplifier in the hair-cell bundle of lizards.

G A Manley et al.

Proceedings of the National Academy of Sciences of the United States of America, 98(5), 2826-2831 (2001-02-28)

Vertebrate sensory hair cells achieve high sensitivity and frequency selectivity by adding self-generated mechanical energy to low-level signals. This allows them to detect signals that are smaller than thermal molecular motion and to achieve significant resonance amplitudes and frequency selectivity

Quantitative determination of dihydrostreptomycin in bovine tissues and milk by liquid chromatography-electrospray ionization-tandem mass spectrometry.

Marc Cherlet et al.

Journal of mass spectrometry : JMS, 42(5), 647-656 (2007-04-19)

Dihydrostreptomycin (DHS) is an aminoglycoside antibiotic used in veterinary medicine in combination with benzylpenicillin for the treatment of bacterial infections in cattle, pigs and sheep. A method to determine its residues in edible tissues of cattle, as well as in

Analysis of impurities in streptomycin and dihydrostreptomycin by hydrophilic interaction chromatography/electrospray ionization quadrupole ion trap/time-of-flight mass spectrometry.

Shin-ichi Kawano

Rapid communications in mass spectrometry : RCM, 23(6), 907-914 (2009-02-19)

Impurities in streptomycin (STR) and dihydrostreptomycin (DHS) were investigated by hydrophilic interaction chromatography/electrospray ionization quadrupole ion trap/time-of-flight mass spectrometry (HILIC/ESI-QIT/TOFMS). Samples were separated on a fused-core silica column (100 mmx2.1 mm i.d., particle size: 2.7 microm) with isocratic elution using

查看所有相關論文

Questions

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務

双氢链霉素 倍半硫酸酯