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34750

Sigma-Aldrich

2,6-二--丁基-4-甲基苯酚

purum, ≥99.0% (GC)

同義詞:

2,6-二-丁基甲酚, BHT, DBPC, 丁基化羟基甲苯, 丁基羟基甲苯

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About This Item

線性公式:
[(CH3)3C]2C6H2(CH3)OH
CAS號碼:
分子量::
220.35
Beilstein:
1911640
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

7.6 (vs air)

品質等級

蒸汽壓力

<0.01 mmHg ( 20 °C)

等級

purum

化驗

≥99.0% (GC)

自燃溫度

878 °F

bp

265 °C (lit.)

mp

68-72 °C
69-73 °C (lit.)

溶解度

methanol: 0.1 g/mL, clear, colorless
methanol: soluble 100 mg/mL, clear, colorless

SMILES 字串

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

InChI 密鑰

NLZUEZXRPGMBCV-UHFFFAOYSA-N

基因資訊

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一般說明

2,6-二-丁基-4-甲基苯酚是一种 4-烷基酚。它是一种抗氧化剂,并表现出通过氧化代谢介导的亲电醌甲醚毒性。它作为 Michael 受体,它与单亲核体和蛋白质的反应已被报道。2,6-二-丁基-4-甲基苯酚与铕 (II)-二苯甲酮二阴离子配合物的反应已有报道。食品添加剂 2,6-二--叔 -丁基-4-甲酚可促进小鼠急性肺毒性和肿瘤生长。

應用

2,6-二--丁基-4-甲酚可用于制备有机铝化合物甲基铝双(2,6-二--丁基-4-烷基酚氧化物)。

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

260.6 °F - open cup

閃點(°C)

127 °C - open cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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M A Lewis et al.
Chemical research in toxicology, 9(8), 1368-1374 (1996-12-01)
4-Alkylphenols, such as the antioxidant 2, 6-di-tert-butyl-4-methylphenol (BHT), exhibit toxicities that appear to be mediated by their oxidative metabolism to electrophilic quinone methides. Reactions of these Michael acceptors with simple nucleophiles and proteins have been reported, but little information is
Methylaluminum bis (2, 6-di-tert-butyl-4-alkylphenoxide). A new reagent for obtaining unusual equatorial and anti-Cram selectivity in carbonyl alkylation.
Maruoka K, et al.
Journal of the American Chemical Society, 107(15), 4573-4576 (1985)
Novel crystal structure of ytterbium (II)-benzophenone dianion complex and its reaction with 2, 6-di-tert-butyl-4-methylphenol.
Hou Z, et al.
Journal of the Chemical Society. Chemical Communications, 9, 722-724 (1999)
Rene Kupfer et al.
Chemical research in toxicology, 15(8), 1106-1112 (2002-08-20)
Acute pulmonary toxicity and tumor promotion by the food additive 2,6-di-tert-butyl-4-methylphenol (BHT) in mice are well documented. These effects have been attributed to either of two quinone methides, 2,6-di-tert-butyl-4-methylenecyclohexa-2,5-dienone (BHT-QM) formed through direct oxidation of BHT by pulmonary cytochrome P450
A M Vijesh et al.
European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized

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