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重要文件

242284

Sigma-Aldrich

苯胺

ACS reagent, ≥99.5%

同義詞:

Aminobenzene, Benzenamine

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About This Item

線性公式:
C6H5NH2
CAS號碼:
分子量::
93.13
Beilstein:
605631
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
eCl@ss:
39030407
PubChem物質ID:
NACRES:
NA.21
等級:
ACS reagent
化驗:
≥99.5%
bp:
184 °C (lit.)
蒸汽壓力:
0.7 mmHg ( 25 °C)
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等級

ACS reagent

品質等級

蒸汽密度

3.22 (185 °C, vs air)

蒸汽壓力

0.7 mmHg ( 25 °C)

化驗

≥99.5%

形狀

liquid

自燃溫度

1139 °F

expl. lim.

11 %

雜質

Hydrocarbons, passes test
Nitrobenzene, passes test (lim. ~0.001%)
≤0.01% chlorobenzene

燃燒殘留物

≤0.005%

折射率

n20/D 1.586 (lit.)

bp

184 °C (lit.)

mp

−6 °C (lit.)

溶解度

water: soluble

密度

1.022 g/mL at 25 °C (lit.)

SMILES 字串

Nc1ccccc1

InChI

1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2

InChI 密鑰

PAYRUJLWNCNPSJ-UHFFFAOYSA-N

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應用

苯胺是一种芳族伯胺,可用作合成3-氯-N-苯基吡啶-2-胺[1]、(Z)-甲基3-(苯基氨基)丁-2-烯酸[2]、2-碘-N-苯基苯甲酰胺[3]、2,4-二氯喹啉[4] N-(2-丙基)苯胺等有机中间体的反应物。[5]

生化/生理作用

苯胺的急性毒性涉及其在体内活化为4-羟基苯胺和与血红蛋白形成加合物。 在红细胞中,这与铁的释放和高铁血红蛋白的积累以及溶血性贫血和脾脏炎症的发展有关。长期给药时,在脾脏中常可观察到肿瘤形成。

物理性質

材料在储存期间变暗成为红棕色,但纯度不会受到影响。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

標靶器官

Blood

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

158.0 °F - closed cup

閃點(°C)

70 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Synthesis of Tetrasubstituted 1H-Pyrazoles by Coppermediated
Coupling of Enaminones with Nitriles
Suri M and Glorius F
Organic Syntheses, 91, 211-220 (2014)
Synthesis of Quinolines by Electrophilic Cyclization of N-(2-Alkynyl)Anilines: 3-Iodo-4-Phenylquinoline
Chen Y, et al
Organic Syntheses, 89, 294-306 (2012)
Synthesis of caboline
He l, et al
Organic Syntheses, 93, 272-285 (2016)
The application of fast scan cyclic voltammetry. Mechanistic study of the initial stage of electropolymerization of aniline in aqueous solutions.
Yang H and Bard AJ.
Journal of Electroanalytical Chemistry, 339(1), 423-449 (1992)
Potassium tert-Butoxide Mediated Synthesis of
Phenanthridinone
Bhakuni BS, et al
Organic Syntheses, 90, 164-173 (2013)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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