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重要文件

114189

Sigma-Aldrich

乙酰氯

reagent grade, 98%

同義詞:

Acetic acid chloride, Acetic chloride, Ethanoyl chloride

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About This Item

線性公式:
CH3COCl
CAS號碼:
分子量::
78.50
Beilstein:
605303
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
eCl@ss:
39050501
PubChem物質ID:
NACRES:
NA.21
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等級

reagent grade

品質等級

蒸汽密度

2.7 (vs air)

蒸汽壓力

11.69 psi ( 20 °C)
32.33 psi ( 55 °C)

化驗

98%

形狀

liquid

自燃溫度

1353 °F

expl. lim.

19 %

折射率

n20/D 1.389 (lit.)

bp

52 °C (lit.)

mp

−112 °C (lit.)

密度

1.104 g/mL at 25 °C (lit.)

官能基

acyl chloride

SMILES 字串

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

InChI 密鑰

WETWJCDKMRHUPV-UHFFFAOYSA-N

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一般說明

乙酰氯可用作烷基化试剂,用于炔烃、烯烃、芳烃、饱和烷烃、烯醇化物和有机金属的亲电乙酰化。[1]

乙酰氯是一种无色的醋酸卤化物。与氨和醇反应,分别生成乙酰胺和乙酰酯。[2]在微波光谱研究中评估了其同位素形态的结构参数和旋转常数。[3]

應用

乙酰氯长期用于 Lepage 和 Roy 脂肪酸分析,以及机器人脂肪酸分析。[4]它可用于氯化氢的定性原位合成。[5]

象形圖

FlameCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

安全危害

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

41.0 °F - closed cup

閃點(°C)

5 °C - closed cup


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Microwave spectrum of acetyl chloride.
Sinnott, KM.
J. Chem. Phys. , 34(3), 851-861 (1961)
Acetyl Chloride-Methanol as a Convenient Reagent for: A) Quantitative Formation of Amine Hydrochlorides B) Carboxylate Ester Formation C) Mild Removal of Nt-Boc-Protective Group.
Nudelman A, et al.
Synthetic Communications, 28(3), 471-474 (1998)
Acetyl Chloride
Pearlman BA
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Yu Hong Lin et al.
Lipids, 47(5), 527-539 (2012-03-21)
Large population studies show that polyunsaturated fatty acids are important for human health, but determining relationships between the health benefits and the fatty acid content has been hampered by the unavailability of labor-effective high-throughput technologies. An automated high throughput fatty
Eagleson M.
Concise Encyclopedia Chemistry, 4-4 (1994)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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