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11772457001

Roche

TUNEL AP

sufficient for 70 tests, solution, pkg of 3.5 mL

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About This Item

分類程式碼代碼:
41105600

形狀

solution

用途

sufficient for 70 tests

包裝

pkg of 3.5 mL

製造商/商標名

Roche

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

TUNEL AP是一种碱性磷酸酶标记的抗体,与TUNEL反应及随后的透射光学显微镜检查合用,可对凋亡(程序性细胞死亡)进行 原位 检测。
加尾反应使用DNA末端转移酶(TdT),又名ISEL(原位末端标记法)或TUNEL(TdT介导的dUTP切口末端标记法),相比使用DNA聚合酶的切口平移标记法(ISNT),有多方面优势:
  • TUNEL对凋亡细胞的标记强度高于ISNT,灵敏度因此也更高。
  • 相比ISNT,TUNEL加核苷酸的速度极为快速。
  • 相对于坏死细胞,TUNEL更偏向于标记凋亡细胞。

應用

TUNEL AP是一种抗体,可将荧光TUNEL分析转换为光学显微镜可检测的比色分析。这种转换是通过抗荧光素抗体与FITC-dUTP的结合而实现的。抗体用碱性磷酸酶(AP)标记。利用沉淀底物(如Fast Red或NBT/BCIP)使AP显色。

成分

抗荧光素抗体,绵羊Fab片段,碱性磷酸酶(AP)标记。即用型溶液。

其他說明

仅用于生命科学研究。不用于诊断操作。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

No data available

閃點(°C)

No data available


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