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SCT046

Sigma-Aldrich

BioTracker CyP AP Live Cell Dye

Live cell imaging dye for alkaline phosphatase (AP) for cancer and stem cell applications.

同義詞:

Live cell imaging probe

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About This Item

分類程式碼代碼:
12352207
NACRES:
NA.47

化驗

≥98% (H-NMR)
≥98% (HPLC)
≥98% (LC/MS)
≥98% (elemental analysis)

技術

cell based assay: suitable

檢測方法

fluorometric

運輸包裝

ambient

一般說明

Alkaline Phosphatase (AP) catalyzes the hydrolysis of the phosphate group in alkaline media. AP is an essential enzyme and widely distributes in a variety of tissues such as liver, intestine, kidney, bone, and placenta. Abnormal AP levels have been shown in numerous cancers, bone disease and liver dysfunction. AP is also expressed by pluripotent stem cells such as ES and IPS cells.

The BioTracker CyP AP dye is a live cell near-infrared (NIR) fluorescent imaging probe for alkaline phosphatase. With its long emission wavelength, the probe is suitable for monitoring AP levels in both in vivo and in vitro tissues and cells. The probe possesses deep tissue penetration, less damage to the biological samples, and lower interference from the background fluorescence compared to other AP probes.

Spectral Properties
Absorbance: 690nm
Emission: 738nm

應用

Live cell fluorescent imaging
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye

品質

Purity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 528.55 g/mol

外觀

Lyophilized

儲存和穩定性

Store BioTracker CyP AP Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Song-Jiao Li et al.
Analytical chemistry, 89(12), 6854-6860 (2017-05-19)
Alkaline phosphatase (ALP) is an essential enzyme and widely distributes in a variety of tissues. To date, various nanomaterial and small-molecule fluorescent probes for ALP have been constructed successfully, but the emission wavelengths of these probes are in the ultraviolet

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