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重要文件

SCC007

Sigma-Aldrich

ReNcell CX人神经祖细胞系

ReNcell CX is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.

同義詞:

Human NSC Line, Human Neural Stem Cell Line, Human Neural Stem Cells

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About This Item

分類程式碼代碼:
41106509
eCl@ss:
32011203
NACRES:
NA.75
暫時無法取得訂價和供貨情況

生物源

human

品質等級

製造商/商標名

Chemicon®
ReNcell

技術

cell culture | stem cell: suitable

輸入

sample type neural stem cell(s)

運輸包裝

liquid nitrogen

一般說明

ReNcell CX是一种永生化的人神经祖细胞系,具有易于分化为神经元和神经胶质细胞的能力。 ReNcell CX源自人胎脑的皮质区域。 通过用c-myc癌基因进行逆转录病毒转导而永生化,该细胞系在层粘连蛋白上以单层快速生长,倍增时间为20-30小时。 核型分析表明,即使经过长时间传代(>45代),ReNcell CX仍可在培养物中保留正常的二倍体核型。 ReNcell CX由ReNeuron Group plc开发,ReNeuron Group plc是一家专门将人体体干细胞用于治疗的生物技术公司。 ReNcell CX可用于多种研究应用,例如神经毒性、神经发生、电生理学、神经递质和受体功能的研究。 ReNcell CX细胞是按照法律和伦理的方式获得的,符合现行的当地知情同意程序。

ReNcell现在用于阿尔茨海默′病的3D细胞模型!
Tanzi, R and Kim, DY et. al. A three-dimensional human neural cell culture model of Alzheimer′s disease.Nature.2014 Nov 13;515(7526):274-8.
发表在Nature上
产品来源:人类皮质脑组织

細胞系描述

神经干细胞

應用

研究类别
干细胞研究

成分

> 1x106 活ReNcell CX细胞

品質

已经验证了每批ReNcell CX细胞的巢蛋白和Sox 2的高水平表达及其自我更新和多谱系分化能力(请参见数据表图)。 通过染色体扩散评估,细胞还显示出正常的核型,并且支原体测试为阴性。已对孕妇血液进行了HIV、HTLV、乙型和丙型肝炎筛查。

儲存和穩定性

当在推荐的储存条件(液氮)下储存时,ReNcell CX细胞在有效期内保持稳定。 请勿暴露于高温下。 到期后,请丢弃所有剩余的试剂。 我们建议在十代内使用细胞。

其他說明

根据产品文件中详述的“学术使用协议”的条款,本产品预期仅用于销售和销售给学术机构,以供内部学术研究使用。有关任何其他用途的信息,请联系[email protected]

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

仅供研究使用。在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Suojun Zhang et al.
International journal of oncology, 45(5), 1989-1996 (2014-09-02)
Glioma stem cells (GSCs), characterized by self-renewal, multi-potentiality and tumorigenicity, are responsible for the tumor propagation, recurrence and resistance to traditional treatments, representing a critical therapeutic target. Neural stem cells (NSCs) possess inherent tropism to brain tumor cells and inhibit
Mia C Borlongan et al.
Neuromolecular medicine, 23(4), 540-548 (2021-04-09)
The present in vitro study showed that IL-2/IL-2R antibody complex facilitates Treg-induced neuroprotection in the oxygen glucose deprivation/reoxygenation (OGD/R) model of stroke. First, we examined the role of IL-2/IL-2R-treated Tregs in OGD/R-exposed rat primary cortical cells (PCCs), which represent the
Qi Gu et al.
Advanced healthcare materials, 5(12), 1429-1438 (2016-03-31)
Direct-write printing of stem cells within biomaterials presents an opportunity to engineer tissue for in vitro modeling and regenerative medicine. Here, a first example of constructing neural tissue by printing human neural stem cells that are differentiated in situ to
Liang Luo et al.
Cells, 10(3) (2021-03-07)
Human adipose-derived stromal cells (ADSCs) are receiving unprecedented attention as a potential cellular source for regenerative medicine-based therapies against various diseases and conditions. However, there still have significant issues concerning the translational development of ADSC-based therapies, such as its heterogeneity
Greg Maguire et al.
Physiological reports, 7(9), e14072-e14072 (2019-05-03)
Evidence suggests that adult stem cell types and progenitor cells act collectively in a given tissue to maintain and heal organs, such as muscle, through a release of a multitude of molecules packaged into exosomes from the different cell types.

文章

ReNcell neural progenitors are immortalized human neural stem cell lines that can differentiate into neurons, astrocytes sand oligodendrocytes.

ReNcell 神經祖細胞是永生化的人類神經幹細胞系,可以分化成神經元、星形細胞和少突細胞。

閱讀幹細胞的類型,包括多能幹細胞、多能幹細胞和 iPSCs,以及它們在基礎幹細胞研究、幹細胞治療和疾病模型中的應用

Read types of stem cells including multipotent stem cells, Pluripotent stem cells and iPSCs and their applications in basic stem cell research, stem cell therapy and disease modelling

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條款

使用 ReNcell 人類神經幹細胞系製造阿爾茨海默氏症 3D NSC 模型的幹細胞培養方案。

A stem cell culture protocol to generate 3D NSC models of Alzheimer’s disease using ReNcell human neural stem cell lines.

Questions

  1. Hello, are these cell lines Puromycin or Hygromycin resistant?

    1 answer
    1. These cell lines were selected using hygromycin resistance.

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