MABN92-AF555

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 555

• 同義詞: Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 555
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 20A12.1, monoclonal
• 物種活性: rat, mouse, human
• 技術: immunohistochemistry: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_001614
• UniProt登錄號: P55008
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... AIF1(199)

描述

一般說明

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

免疫原

Linear peptide corresponding to a human Iba1/AIF1 sequence.

應用

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.

品質

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:150 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

標靶描述

~17 kDa observed

外觀

Protein G Purified

Purified mouse antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable