MABN92-AF488

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 488

• 同義詞: Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 488
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 20A12.1, monoclonal
• 物種活性: human, mouse, rat
• 技術: immunohistochemistry: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_001614
• UniProt登錄號: P55008
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... AIF1(199)

描述

一般說明

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

應用

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

品質

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

標靶描述

~17 kDa observed

其他說明

Concentration: Please refer to lot specific datasheet.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable