MABD120

Anti-FGFR4 Antibody, clone 4H2B10B2

ascites fluid, clone 4H2B10B2, from mouse

• 同義詞: Fibroblast growth factor receptor
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: ascites fluid
• 抗體產品種類: primary antibodies
• 無性繁殖: 4H2B10B2, monoclonal
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgG1
• UniProt登錄號: P22455
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... FGFR4(2264)

描述

一般說明

FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that plays an important role in the biological functions of specific growth factors. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

The previously assigned protein identifier G3JVM2 has been merged into P22455. Full details can be found on the UniProt database.

免疫原

Purified recombinant fragment of human FGFR4 expressed in E. Coli.

應用

Detect FGFR4 using this mouse monoclonal antibody, Anti-FGFR4 Antibody, clone 4H2B10B2 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected FGFR4 in human liver tissue.

Optimal working dilutions must be determined by end user.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

品質

Evaluated by Western Blotting in HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA .

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected FGFR4 in HEK293T cells transfected with pCMV6-ENTRY FGFR4 cDNA.

標靶描述

~88 kDa observed

外觀

Unpurified

Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable