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重要文件

MAB1962

Sigma-Aldrich

Anti-Integrin β2 Antibody, clone P4H9

clone P4H9, Chemicon®, from mouse

同義詞:

CD18

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

P4H9, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

同型

IgG3

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ITGB2(3689)

相關類別

特異性

beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.

應用

Detect Integrin β2 using this Anti-Integrin β2 Antibody, clone P4H9 validated for use in IH.
Research Category
Cell Structure
Research Sub Category
Integrins
Suitable for use in immunofluorescence at 1:1000.

Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.

For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.

外觀

Format: Purified
Non-sterile buffer of 0.02M phosphate, 0.25M Sodium Chloride, pH 7.6,

0.1% sodium azide.

儲存和穩定性

Maintain between 2 and 8°C.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Elzbieta Pluskota et al.
The Journal of biological chemistry, 279(17), 18063-18072 (2004-02-11)
Plasmin, the pivotal thrombolytic enzyme, is generated on the surface of many cell types, where urokinase receptor (uPAR)-bound urokinase (uPA) activates cell-bound plasminogen (Plg). It has been reported that neutrophils mediate endogenous thrombolysis involving a uPA-dependent mechanism, and we previously
I N Gavrilovskaya et al.
Journal of virology, 73(5), 3951-3959 (1999-04-10)
Hantaviruses replicate primarily in the vascular endothelium and cause two human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). In this report, we demonstrate that the cellular entry of HFRS-associated hantaviruses is facilitated by specific integrins
Elzbieta Pluskota et al.
Blood, 101(4), 1582-1590 (2002-10-24)
Previous studies demonstrated that integrin alpha(M)beta(2) (CD11b/18, Mac-1) forms a physical complex with the urokinase-type plasminogen activator receptor (uPAR/CD87) on leukocytes. In this study, we used human peripheral blood neutrophils and transfected cells expressing alpha(M)beta(2), uPAR, or both receptors to
Yukinori Endo et al.
Cell adhesion & migration, 12(2), 93-100 (2016-10-08)
Anosmin is an extracellular matrix protein, and genetic defects in anosmin result in human Kallmann syndrome. It functions in neural crest formation, cell adhesion, and neuronal migration. Anosmin consists of multiple domains, and it has been reported to bind heparan
Chia-Hsiang Yen et al.
Marine drugs, 17(12) (2019-11-28)
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