Galactocerebroside (GalC) is a major galactosphingolipid of myelin which plays a role in myelination. GalC is a very useful, specific marker for oligodendroglial lineage.
特異性
Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cells.
免疫原
Synaptic plasma membranes from bovine hippocampus.
應用
Detect Galactocerebroside using this Milli-Mark Anti-Galactocerebroside-FITC Antibody, clone mGalC validated for use in FC.
Research Category Neuroscience
Research Sub Category Neuronal & Glial Markers
品質
Evaluated by flow cytometry using PC-12 cells.
外觀
Protein A purified
Purified mouse monoclonal IgG3 conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
儲存和穩定性
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析報告
Control PC-12 cells
法律資訊
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Molecular and behavioral responses to opioids are thought to be primarily mediated by neurons, although there is accumulating evidence that other cell types play a prominent role in drug addiction. To investigate cell-type-specific opioid responses, we performed single-cell RNA sequencing
Proceedings of the National Academy of Sciences of the United States of America, 118(40) (2021-09-30)
RNA polymerase (Pol) III synthesizes abundant short noncoding RNAs that have essential functions in protein synthesis, secretion, and other processes. Despite the ubiquitous functions of these RNAs, mutations in Pol III subunits cause Pol III-related leukodystrophy, an early-onset neurodegenerative disease.
