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FCABS400F

Sigma-Aldrich

Milli-Mark® 抗-FcεRI抗体,γ 亚基-FITC

Milli-Mark®, from rabbit

同義詞:

Fc fragment of IgE high affinity I receptor for gamma polypeptide, Fc-epsilon RI-gamma, FceRI gamma, IgE Fc receptor subunit gamma, Immunoglobulin E receptor, high affinity,gamma chain

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

品質等級

共軛

FITC conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human, rat

製造商/商標名

Milli-Mark®

技術

flow cytometry: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FCER1G(2207)

一般說明

I型过敏反应是通过IgE高亲和受体(FceRI)介导的。当呈递多价抗原时,单体IgE FceRI受体复合物的重新分布会导致肥大细胞和嗜碱性粒细胞脱粒,从而导致随后释放引起I型过敏反应的因子。FceRI受体是四聚体复合物,由a链,b链和二聚体g链组成。尽管a链主要参与IgE的结合,但信号通过g亚基转移,g亚基包含免疫受体酪氨酸激活基序(ITAM),对于通过Syk和Lyn酪氨酸激酶启动受体介导的信号转导至关重要。FceRI受体能够与IgE结合和脱离,为研究激酶偶联受体的性能提供了通用模型。

特異性

可识别并特异于FcεRI,γ-亚基。

免疫原

与Fc受体γ亚基的80-86氨基酸对应的合成肽。

應用

Milli-Mark 抗-FcεRI抗体,γ亚基-FITC是针对FcεRI的抗体,用于FC。
研究子类别
炎症 & 自身免疫机制
研究类别
炎症 & 免疫学

品質

通过流式细胞术对RBL细胞进行了评估

標靶描述

计算值为10 kDa

外觀

在含0.1%叠氮化钠和15 mg/mL BSA的PBS中与FITC偶联的纯化的兔多克隆IgG。
纯化的蛋白 A

儲存和穩定性

自收到之日起,未稀释等分试样避光冷藏于 2-8°C,可保存6个月。

分析報告

对照
RBL细胞

其他說明

已证明非偶联抗体(目录编号06-727)对人和小鼠有效。
最佳工作稀释度必须由其它仪器的最终用户进行确定。

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Elena Woods et al.
NPJ vaccines, 6(1), 117-117 (2021-09-30)
Effective vaccines for human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) remain a significant challenge for these infectious diseases. Given that the innate immune response is key to controlling the scale and nature of developing adaptive immune responses, targeting
Robin J Dart et al.
Science (New York, N.Y.), 381(6663), eadh0301-eadh0301 (2023-09-14)
Murine intraepithelial γδ T cells include distinct tissue-protective cells selected by epithelial butyrophilin-like (BTNL) heteromers. To determine whether this biology is conserved in humans, we characterized the colonic γδ T cell compartment, identifying a diverse repertoire that includes a phenotypically
Kombo F N'guessan et al.
Frontiers in immunology, 15, 1339727-1339727 (2024-02-29)
The RV144 Thai phase III clinical trial's canarypox-protein HIV vaccine regimen showed modest efficacy in reducing infection. We therefore sought to determine the effects of vaccine administration on innate cell activation and subsequent associations with vaccine-induced immune responses. RV306 was
Diana Rasoulouniriana et al.
Cancer immunology research, 11(6), 792-809 (2023-04-19)
The pioneering design of chimeric antigen receptor (CAR) T-cell therapy demonstrated the potential of reprogramming the immune system. Nonetheless, T-cell exhaustion, toxicity, and suppressive microenvironments limit their efficacy in solid tumors. We previously characterized a subset of tumor-infiltrating CD4+ T
Moriya Gamliel et al.
Immunity, 48(5), 951-962 (2018-05-17)
Natural killer cells (NKs) are abundant in the human decidua, regulating trophoblast invasion and angiogenesis. Several diseases of poor placental development are associated with first pregnancies, so we thus looked to characterize differences in decidual NKs (dNKs) in first versus

文章

Troubleshooting guide offers solutions for common flow cytometry problems, ensuring improved analysis performance.

流式細胞儀染料選擇提示可將螢光劑與流式細胞儀配置相匹配,從而提高面板性能。

Flow cytometry dye selection tips match fluorophores to flow cytometer configurations, enhancing panel performance.

故障排除指南提供常見流式細胞計數問題的解決方案,確保改善分析效能。

條款

Learn key steps in flow cytometry protocols to make your next flow cytometry experiment run with ease.

Explore our flow cytometry guide to uncover flow cytometry basics, traditional flow cytometer components, key flow cytometry protocol steps, and proper controls.

探索我們的流式細胞計量指南,瞭解流式細胞計量基礎知識、傳統流式細胞計量儀元件、主要流式細胞計量協議步驟以及正確的控制方法。

了解流式細胞計量協議的關鍵步驟,讓您輕鬆進行下一次流式細胞計量實驗。

Questions

  1. what is the concentration of this antibody (FCABS400F)

    1 answer
    1. The concentration of this product is dependent on the lot. For specific lot concentration information, contact the local Technical Service department. For instance, lot number 4138071 has a concentration of 0.1 mg/mL.

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