FCABS165A6

Milli-Mark^® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

Milli-Mark^®, from rabbit

• 同義詞: Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, MAP kinase isoform p44, p44, MAPK, Microtubule-associated protein 2 kinase, MNK1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 647
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: human
• 製造商／商標名: Milli-Mark^®
• 技術: flow cytometry: suitable
• NCBI登錄號: NP_059043
• UniProt登錄號: P21708
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MAPK1(5594)

描述

一般說明

The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.

特異性

Antibody recognizes MAPK1/2. C-terminus.

免疫原

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.

應用

Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.

Research Category
Signaling

Research Sub Category
MAP Kinases

品質

Evaluated by flow cytometry using Jurkat cells

標靶描述

43 kDa Calculated

外觀

Protein A purified

Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide

儲存和穩定性

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

分析報告

Control
Jurkat cells

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable