ABT277

Anti-Galectin-7 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Galectin-7, Gal-7, HKL-14, PI7, p53-induced gene 1 protein
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 300
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 物種活性（以同源性預測）: chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology), monkey (based on 100% sequence homology), baboon (based on 100% sequence homology)
• 技術: immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_001035972
• UniProt登錄號: P47929
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... LGALS7B(653499)

描述

一般說明

Galectins are a family of carbohydrate binding proteins. Galectin-7 was initially isolated from human keratinocytes as a novel member of S-lectin family that was responsive to retinoic acid but not detectable in epidermal tumors or squamous carcinomas. It is an early transcriptional target of the tumor suppressor P53 and inducible by UV radiation as well. Galectin-7 is also an enhancer of apoptosis, whereas galectin-1 induces tumorigenicity and resistance to apoptosis in several types of cancers. Recent research demonstrates that Galectin-7 acts as an adhesion molecule during implantation, and increased expression of Galectin-7 is associated with miscarriage, thus Galectin-7 is also being studied as a possible biomarker for miscarriage prediction.

免疫原

KLH-conjugated beta-galactose binding region corresponding to human Galectin-7.

應用

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Galectin-7 in human skin and human larynx tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

This Anti-Galectin-7 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-7.

品質

Evaluated by Western Blotting in human skin tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-7 in 10 µg of human skin tissue lysate.

標靶描述

~16 kDa observed

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids