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AB9084

Sigma-Aldrich

抗多囊肾蛋白L抗体

serum, Chemicon®

同義詞:

Anti-PCL, Anti-PKD2L, Anti-PKDL, Anti-TRPP3

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Pkd2(18764)

特異性

多囊肾蛋白L

免疫原

来自人多囊肾蛋白L1的N末端的合成肽。

應用

研究子类别
肾生理学
研究类别
代谢
蛋白质印迹:使用ECL为1:1,000。抗体与90 kDa 多囊肾蛋白L1反应。建议的封闭缓冲液为10%正常山羊血清(或与你的二抗相同的宿主),1%BSA的含0.05%吐温20的0.1 M PBS。建议的稀释缓冲液为1%正常山羊血清(或与你的二抗相同的宿主),1%BSA的含0.05%吐温20的0.1 M PBS。优选的凝胶百分比是4-12%梯度凝胶。

免疫细胞化学:1:1,000

免疫组化:使用荧光标记的二抗在2-8°C下以1:1,000过夜。建议的固定剂是0.1 M PBS中的4%多聚甲醛(一小时)。建议的透化方法是0.05%Triton X-100稀释缓冲液。建议的封闭缓冲液为10%正常山羊血清(或与你的二抗相同的宿主)和1%BSA的0.1 M PBS。建议的稀释缓冲液为1%正常山羊血清(或与你的二抗相同的宿主)和1%BSA的0.1 M PBS。

最佳工作稀释度必须由最终用户进行确定。
该抗多囊肾蛋白L抗体经过验证可用在 WB、IC、IH 中检测 多囊肾蛋白L1。

分析報告

对照
阳性对照:成年小鼠视网膜

阴性对照:成年小鼠肺

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Qiang Su et al.
Nature communications, 12(1), 4871-4871 (2021-08-13)
The heteromeric complex between PKD1L3, a member of the polycystic kidney disease (PKD) protein family, and PKD2L1, also known as TRPP2 or TRPP3, has been a prototype for mechanistic characterization of heterotetrametric TRP-like channels. Here we show that a truncated
Zuzana Tonelli Gombalová et al.
The Journal of comparative neurology, 528(15), 2523-2550 (2020-03-27)
Cerebrospinal fluid contacting neurons (CSF-cNs) represent a specific class of neurons located in close vicinity of brain ventricles and central canal. In contrast with knowledge gained from other vertebrate species, we found that vast majority of CSF-cNs in the spinal
Yumi Ueki et al.
Disease models & mechanisms, 11(7) (2018-06-23)
Familial dysautonomia (FD) is an autosomal recessive disorder marked by developmental and progressive neuropathies. It is caused by an intronic point-mutation in the IKBKAP/ELP1 gene, which encodes the inhibitor of κB kinase complex-associated protein (IKAP, also called ELP1), a component
Zongshi Lu et al.
Cell reports, 24(6), 1639-1652 (2018-08-09)
High salt intake is one independent risk factor for cardiac hypertrophy. Polycystic kidney disease 2-like 1 (PKD2L1, also called TRPP3) acts as a sour sensor in taste cells, and its possible role in the cardiovascular system is unknown. Here, we
Fang Sun et al.
Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 1349-1358 (2020-05-20)
High-sensitivity C-reactive protein (hs-CRP) has been regarded as a biomarker of low-degree inflammation in illness; however, whether CRP exerts its pathogenic effect on the cardiometabolic system remains unknown. Aside from the beneficial effects of metabolic surgery on cardiometabolic system, its impact

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