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Merck

8.17043

SAFC

硫柳汞

EMPROVE® ESSENTIAL, Ph. Eur., BP

製藥生產

同義詞:

Thimerosal

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About This Item

經驗公式(希爾表示法):
C9H9HgNaO2S
CAS號碼:
分子量::
404.81
MDL號碼:
分類程式碼代碼:
12352103
酶委員會索引編號:
200-210-4

agency

BP
Ph. Eur.

品質等級

產品線

EMPROVE® ESSENTIAL

形狀

solid

pH值

6.7 (20 °C, 10 g/L in H2O)

mp

232-233 °C (decomposition)

轉變溫度

flash point 250 °C

溶解度

1000 g/L

應用

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation

儲存溫度

15-25°C

InChI

1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

InChI 密鑰

RTKIYNMVFMVABJ-UHFFFAOYSA-L

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Thimerosal has strong antiseptic and antifungal capabilities and is therefore typically used as preservative in liquid dosage forms of cosmetics and pharmaceutical products.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

As part of the corporation global plan to support the MinamataConvention in eliminating mercury-containing compounds, as of January 2021customers will be required to provide an End-Use Declaration. The sales ofthimerosal will be restricted for approved applications only, such aspreservative in vaccine manufacturing, preservative in eye cosmetics, researchuse within academia (excluding preservation intent) and as reference materialonly. The product is not intended for use as a biocide under global biocideregulations, including but not limited to US EPA′s Federal InsecticideFungicide and Rodenticide Act , European Biocidal Products Regulation, Canada’sPest Management Regulatory Agency, Turkey’s BiocidalProducts Regulation, Korea’s Consumer Chemical Products and BiocideSafety Management Act (K-BPR) and others.

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

標靶器官

Kidney

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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