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Merck
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重要文件

662045

Sigma-Aldrich

Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb

liquid, Calbiochem®

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

不包含

preservative

物種活性

human, rat, mouse

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG

運輸包裝

wet ice

儲存溫度

−70°C

目標翻譯後修改

unmodified

基因資訊

human ... UCP1(7350)

一般說明

Protein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
Recognizes the UCP-1 protein.
This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).

免疫原

Mouse
a synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1

應用

Immunoblotting (1:1000)

警告

Toxicity: Standard Handling (A)

外觀

In PBS.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Does not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Traci A Czyzyk et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1151-1159 (2009-11-18)
General opioid receptor antagonists reduce food intake and body weight in rodents, but the contributions of specific receptor subtypes are unknown. We examined whether genetic deletion of the kappa-opioid receptor (KOR) in mice alters metabolic physiology. KOR-knockout (KO) and wild-type
Laurent Vergnes et al.
The Journal of clinical endocrinology and metabolism, 101(11), 4440-4448 (2016-11-05)
Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by the pheo tumors.
Traci A Czyzyk et al.
American journal of physiology. Endocrinology and metabolism, 305(2), E282-E292 (2013-05-30)
Obesity continues to be a global health problem, and thus it is imperative that new pathways regulating energy balance be identified. Recently, it was reported: (Hayashi K, Cao T, Passmore H, Jourdan-Le Saux C, Fogelgren B, Khan S, Hornstra I
Marcella Funicello et al.
PloS one, 2(8), e683-e683 (2007-08-02)
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white adipose tissue (WAT) of obese individuals. We herein characterized the
C L Plaisier et al.
Nutrition & diabetes, 2, e46-e46 (2013-03-01)
A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity

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