推薦產品
化驗
≥95% (SDS-PAGE)
品質等級
形狀
liquid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
avoid repeated freeze/thaw cycles
雜質
<0.1 EU/μg endotoxin (EU/μg TRAIL)
運輸包裝
wet ice
儲存溫度
−70°C
一般說明
Recombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.
生化／生理作用
Induces apoptosis in U937 cells at 1 μg/ml within 5 h.
包裝
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
外觀
In 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.
重構
Following initial thaw, aliquot and freeze
(-70°C).
(-70°C).
其他說明
Lin, Y., et al. 2000. Mol. Cell. Biol.20, 6638.
Mitsaides, N., et al. 2000. Cancer Res.60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med.189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol.137, 221.
Pan, G., et al. 1997. Science276, 111.
Pan, G., et al. 1997. Science277, 815.
Sheridan, J.P., et al. 1997. Science277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem.271, 12687.
Wiley, S.R., et al. 1995. Immunity3, 673.
Mitsaides, N., et al. 2000. Cancer Res.60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med.189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol.137, 221.
Pan, G., et al. 1997. Science276, 111.
Pan, G., et al. 1997. Science277, 815.
Sheridan, J.P., et al. 1997. Science277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem.271, 12687.
Wiley, S.R., et al. 1995. Immunity3, 673.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Oliver H Voss et al.
Cell death & disease, 12(4), 287-287 (2021-03-19)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selective killing of cancer cells underlines its anticancer potential. However, poor tolerability and resistance underscores the need to identify cancer-selective TRAIL-sensitizing agents. Apigenin, a dietary flavonoid, sensitizes lung cancer cell lines to TRAIL. It
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