567570

Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure.

• 同義詞: Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.
• 經驗公式（希爾表示法）: C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
• CAS號碼: 22189-32-8
• 分子量：: 495.35
• MDL號碼: MFCD00150886
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white to off-white
• 溶解度: water: 50 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
• InChI 密鑰: DCHJOVNPPSBWHK-UXXUFHFZSA-N

描述

一般說明

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire’s disease) kinase and expressed in E. coli. Potency: ≥500 µg/mg.

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire′s disease) kinase and expressed in E. coli.

生化／生理作用

Primary Target
Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure

警告

Toxicity: Standard Handling (A)

其他說明

Thompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable