5.04359

Palmitoylethanolamide

• 同義詞: Palmitoylethanolamide, N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
• 經驗公式（希爾表示法）: C₁₈H₃₇NO₂
• CAS號碼: 544-31-0
• 分子量：: 299.49
• MDL號碼: MFCD00020562
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 化驗: ≥99% (HPLC)
• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white
• 溶解度: DMSO: 20 mM
• 儲存溫度: −20°C
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
• InChI 密鑰: HXYVTAGFYLMHSO-UHFFFAOYSA-N

描述

一般說明

An endogenous lipid that acts as a selective agonist for GPR55 receptors (EC₅₀ = 4, 19 800 and >30 000 nM at GPR55, CB₂ and CB₁ receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC₅₀ = 3 µM).

生化／生理作用

Primary Target
GPR55 receptor

警告

Toxicity: Standard Handling (A)

準備報告

Slight warming is required for complete solubilization.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther.292, 886.

Lambert, D., et al. 2001. Epilepsia.42, 321.
Lambert, D., et al. 2002. Curr. Med. Chem.9, 663.
Lo Verme, J., et al. 2005. Life Sci.77, 1685.
Re, G., et al. 2005. Vet. J.173, 21.
Ryberg, R., et al. 2007. Br. J. Pharmacol.152, 1092.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05,GHS09
• 訊號詞: Danger
• 危險聲明: H315 - H318 - H411
• 防範說明: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• 危險分類: Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable