495417-M

N-Oleoyl Ethanolamine

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

• 同義詞: N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
• 經驗公式（希爾表示法）: C₂₀H₃₉NO₂
• CAS號碼: 111-58-0
• 分子量：: 325.53
• MDL號碼: MFCD00045972
• 分類程式碼代碼: 12352211

屬性

• 品質等級: 100
• 化驗: ≥98% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: chloroform: 5 mg/mL; ethanol: 5 mg/mL; methanol: 5 mg/mL
• 儲存溫度: −20°C
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• InChI 密鑰: BOWVQLFMWHZBEF-KTKRTIGZSA-N

描述

一般說明

A potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

生化／生理作用

Primary Target
Acid ceramidase

Target IC₅₀: ~ 500 µM against acid ceramidase

警告

Toxicity: Standard Handling (A)

其他說明

Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable