推薦產品
產品名稱
夹竹桃麻素, A cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase.
品質等級
描述
Merck USA index - 14, 741
化驗
≥98% (GC)
形狀
powder
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
white to off-white
溶解度
DMSO: 10 mg/mL
ethanol: 20 mg/mL
運輸包裝
ambient
儲存溫度
−20°C
SMILES 字串
O(C)c1c(ccc(c1)C(=O)C)O
InChI
1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI 密鑰
DFYRUELUNQRZTB-UHFFFAOYSA-N
一般說明
一种细胞可透过性抗炎酚类化合物，可作为 NADPH 氧化酶的有效和选择性抑制剂。研究表明，可阻断鼠巨噬细胞中过亚硝酸盐的形成。据报道，可通过激活 AP-1 增加谷胱甘肽的合成。还有有报道表明，可防止巨噬细胞（10 mM）吞噬髓磷脂。
生化／生理作用
主靶
NADPH 氧化酶
NADPH 氧化酶
产物不与ATP竞争。
可逆：否
细胞可渗透性：具有
包裝
用惰性气体包装
警告
毒性：刺激性（B）
重構
重悬后，等分并冷冻（-20°C）。储备溶液在-20°C下可稳定保存至多6个月。
其他說明
Abid, M.R., et al. 2000.FEBS Lett.486, 252.
Muijsers, R.B., et al. 2000.Br. J. Pharmacol.130, 932.
Lapperre, T.S., et al. 1999.FEBS Lett.443, 235.
Supinski, G., et al. 1999, J. Appl. Physiol.87, 776.
van der Goes, A., et al. 1998.J. Neuroimmunol.92, 67.
Hart, B.A., and Simmons, J.M.1992.Biotechnol.Ther.3, 3.
Muijsers, R.B., et al. 2000.Br. J. Pharmacol.130, 932.
Lapperre, T.S., et al. 1999.FEBS Lett.443, 235.
Supinski, G., et al. 1999, J. Appl. Physiol.87, 776.
van der Goes, A., et al. 1998.J. Neuroimmunol.92, 67.
Hart, B.A., and Simmons, J.M.1992.Biotechnol.Ther.3, 3.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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