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Merck

1.08694

SAFC

Deviron® 13-S9

Detergent, EMPROVE® EXPERT

製藥生產

同義詞:

Alcohols, C11-15-secondary, ethoxylated

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About This Item

經驗公式(希爾表示法):
CH3(CH2)nCH(CH2)mCH3O(CH2CH2O)xH
分類程式碼代碼:
12352200
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品質等級

產品線

EMPROVE® EXPERT

應用

pharma/biopharma processes

儲存溫度

15-25°C

一般說明

Detergents, such as non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Detergent-mediated viral inactivation is widely used in multiple biotherapeutic production processes to ensure meeting regulatory requirements for viral safety.

Our SAFC portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC portfolio of high-quality products withstands strict quality control procedures.

應用

REACH compliantdetergent used in viral inactivation or cell lysis.

包裝

1.08694.1000 / 1L / Glass bottle

1.08694.2500 / 2.5L / Glass bottle

1.08694.9025 / 25L / PE container

法律資訊

DEVIRON is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

469.4 °F - open cup

閃點(°C)

243 °C - open cup


什麼是Emprove® 套裝?

Emprove® 計劃是一個為我們的篩選器和單次用元件、製藥原料和起始材料提供全面徹底記錄的系統。

Material Qualification Dossier

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Operational Excellence Dossier

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Operational Excellence Dossier

可透過訂閱或付費取得

Operational Excellence Dossier

可透過訂閱或付費取得

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Emprove® 檔案包含旨在支持藥品生產商的註冊過程和風險評估活動的訊息,並包含機密資訊。如果您想存取,請聯絡我們

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文章

本頁說明了細胞裂解的主要注意事項,以及在 AAV 媒體製造過程中,如何結合高鹽濃度和耐鹽內切酶來提高載體滴度和感染性。

This page describes key considerations for cell lysis and how the combination of a high salt concentration and a salt tolerant endonuclease can be used to increase vector titer and infectivity during AAV vector manufacturing.

相關內容

The use of Benzonase® endonuclease can significantly reduce the levels of DNA by more than 100,000-fold while also reducing viscosity and protecting downstream equipment from DNA fouling. However, optimization strategies and DoE are critical when it comes to reducing DNA in your process. Setting up a DoE for your Benzonase® endonuclease application can help you find the optimal operation conditions that deliver the required DNA clearance from your process.

Learn more on mAb downstream processing, more specifically virus inactivation and the relevant associated products.

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