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Merck
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文件

06-676

Sigma-Aldrich

Anti-mGluR2/3 Antibody

Upstate®, from rabbit

同義詞:

Anti-GLUR2, Anti-MGLUR2, Anti-mGlu2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human, rat

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

rat ... Grm2(24415)

特異性

mGluR2 and mGluR3

免疫原

peptide (KQFVPTVCNGREVVDSTTSSL) corresponding to amino acids 853-872 of human metabotropic glutamate receptor 2

應用

Anti-mGluR2/3 Antibody is an antibody against mGluR2/3 for use in IH, IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neurodegenerative Diseases

品質

routinely evaluated by immunoblot on rat brain microsomal preparation

標靶描述

100-110kDa

外觀

Protein A chromatography
0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol
Format: Purified

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.
Dhanya, RP; Sheffler, DJ; Dahl, R; Davis, M; Lee, PS; Yang, L; Nickols, HH; Cho et al.
Journal of medicinal chemistry null
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.
Shigemoto, R, et al.
The Journal of Neuroscience, 17, 7503-7522 (1997)
L Emile et al.
Neuropharmacology, 35(5), 523-530 (1996-05-01)
Glutamic acid is the major excitatory amino acid of the central nervous system which interacts with two receptor families, the ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are coupled to G proteins and can be divided into
Yoshiaki Miyamoto et al.
The international journal of neuropsychopharmacology, 20(12), 1027-1035 (2017-10-12)
Several clinical studies have suggested that N-acetylaspartate and N-acetylaspartylglutamate levels in the human brain are associated with various psychiatric disorders, including major depressive disorder. We have previously identified Shati/Nat8l, an N-acetyltransferase, in the brain using an animal model of psychosis.
M Behnam Ghasemzadeh et al.
Pharmacology, biochemistry, and behavior, 92(3), 383-392 (2009-01-13)
Glutamatergic neurotransmission plays an important role in the behavioral and molecular plasticity observed in cocaine mediated locomotor sensitization. Recent studies show that glutamatergic signaling is regulated by receptor trafficking, synaptic localization, and association with scaffolding proteins. The trafficking of the

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