06-1041

Anti-RIG-I, CT Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Probable ATP-dependent RNA helicase DDX58, DEAD box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: western blot: suitable
• NCBI登錄號: NP_055129
• UniProt登錄號: O95786
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... DDX58(23586)

描述

一般說明

Retinoic acid-inducible gene 1 (RIG-1, DDX58) is a cytoplasmic protein belonging to the family of RIG-1-like receptor (RLR) family. It is a multidomain protein containing an N-terminal caspase recruitment domain (CARD); a DExD/H box helicase domain; and a C-terminal repression domain. RIG-1 has a well-documented role in innate immunity, as a virus-sensing protein that detects viral RNA molecules and induces the production of IFN-β through activation of the inflammasome complex.

特異性

This antibody recognizes the C-terminus of RIG-I.

免疫原

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human RIG-I.

應用

Anti-RIG-I, C-terminus Antibody is an antibody against RIG-I, C-terminus for use in Western Blotting.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

品質

Evaluated by Western Blot in untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for 12 hours.

Western Blot Analysis: 1 µg/mL of this antibody detected RIG-I in 10 µg of untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours..

標靶描述

~102 kDa observed

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable