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Merck
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05-579

Sigma-Aldrich

Anti-Endostatin Antibody, clone 1837.46

clone 1837.46, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

1837.46, monoclonal

物種活性

mouse, human

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Col18A1(12822)

特異性

endostatin

免疫原

Full-length recombinant murine endostatin

應用

Anti-Endostatin Antibody, clone 1837.46 is an antibody against Endostatin for use in WB, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

品質

routinely evaluated by immunoblot on 3T3 cell lysates

標靶描述

Recognizes endostatin, Mr 22kDa An unidentified protein is also weakly detected at Mr 54kDa

外觀

Thiophilic chromatography
50mM sodium phosphate, pH 8.0, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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B V Sauter et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4802-4807 (2000-04-12)
Inhibition of angiogenesis has been shown to be an effective strategy in cancer therapy in mice. However, its widespread application has been hampered by difficulties in the large-scale production of the antiangiogenic proteins. This limitation may be resolved by in
M C Cichy et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 42(12), 1150-1155 (2009-11-07)
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation
H M Strik et al.
Cancer, 91(5), 1013-1019 (2001-03-17)
Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been examined in human brain tumors. The authors report the production of a monoclonal antibody and detection of endostatin in
M Dhanabal et al.
The Journal of biological chemistry, 274(17), 11721-11726 (1999-04-17)
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Gunsalus, KT; Wagoner, MP; Meyer, K; Potter, WB; Schoenike, B; Kim, S; Alexander et al.
Cancer Research null

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