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重要文件

04-080

Sigma-Aldrich

抗-BAF250a/ARID1a抗体,克隆PSG3

clone PSG3, Upstate®, from mouse

同義詞:

Anti-B120, Anti-BAF250, Anti-BAF250a, Anti-BM029, Anti-C1orf4, Anti-CSS2, Anti-ELD, Anti-MRD14, Anti-OSA1, Anti-P270, Anti-SMARCF1, Anti-hELD, Anti-hOSA1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
PSG3, monoclonal
application:
IF
WB
物種活性:
human
技術:
immunofluorescence: suitable
western blot: suitable
citations:
16
暫時無法取得訂價和供貨情況

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

PSG3, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

immunofluorescence: suitable
western blot: suitable

同型

IgG

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... ARID1A (8289)

特異性

BAF250a/ARID1a

免疫原

GST融合蛋白,对应人BAF250a/ARID1a中部419个残基。

應用

抗BAF250a/ARID1A抗体,克隆PSG3是针对BAF250a/ARID1A的抗体,用于WB,ChIP,IC & IHC。
研究子类别
染色质生物学

转录因子
研究类别
表观遗传学&核功能

品質

已通过免疫印迹进行常规评估。

標靶描述

~270 kDa

外觀

100 μg蛋白A纯化的小鼠单克隆IgG,溶于100 μL 1X PBS(pH 7.0,0.1%叠氮化物)中。
形式:纯化
蛋白A纯化

儲存和穩定性

自运送之日起在-20°C下保存2年

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
Chandler, RL; Damrauer, JS; Raab, JR; Schisler, JC; Wilkerson, MD; Didion, JP; Starmer et al.
Nature Communications null
Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression.
Xu, F; Flowers, S; Moran, E
The Journal of Biological Chemistry null
Radhika Mathur et al.
Nature genetics, 49(2), 296-302 (2016-12-13)
Genes encoding subunits of SWI/SNF (BAF) chromatin-remodeling complexes are collectively mutated in ∼20% of all human cancers. Although ARID1A is the most frequent target of mutations, the mechanism by which its inactivation promotes tumorigenesis is unclear. Here we demonstrate that
Guillermo Pablo Vicent et al.
The Journal of biological chemistry, 285(4), 2622-2631 (2009-11-27)
Steroid hormones induce transcription of their responsive genes by complex mechanisms including synergism between the hormone receptors and other transcription factors. On the mouse mammary tumor virus (MMTV) promoter progesterone induction is mediated by the reciprocal synergism between progesterone receptor
Xiaomei Wang et al.
The Biochemical journal, 383(Pt 2), 319-325 (2004-06-02)
p270 (ARID1A) is a member of the ARID family of DNA-binding proteins and a subunit of human SWI/SNF-related complexes, which use the energy generated by an integral ATPase subunit to remodel chromatin. ARID1B is an independent gene product with an

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