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Merck
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M1570

Sigma-Aldrich

抗肌球蛋白(骨骼肌,快速)抗体，小鼠单克隆抗体

enhanced validation

clone MY-32, purified from hybridoma cell culture

同義詞:

单克隆抗肌球蛋白（骨骼肌快肌） 小鼠抗

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About This Item

MDL號碼:
MFCD00145920
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

200

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

MY-32, monoclonal

形狀

buffered aqueous solution

物種活性

rat, chicken, rabbit, mouse, human, bovine, guinea pig, feline

包裝

antibody small pack of 25 μL

加強驗證

independent
Learn more about Antibody Enhanced Validation

濃度

~1.0 mg/mL

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 10-20 μg/mL using porcine tongue
microarray: suitable
western blot: 0.5-1.0 μg/mL using total extract of rabbit skeletal muscle

同型

IgG1

UniProt登錄號

P12882

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MYH1(4619) , MYH2(4620)
mouse ... Myh1(17879) , Myh2(17882)
rat ... Myh1(287408) , Myh2(691644)

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相關類別

一般說明

定位于肌球蛋白重链上的表位。可对骨骼肌中发现的快速（II型）和新生儿肌动蛋白分子进行染色，但不会对培养细胞中的心肌、平滑肌或非肌肉肌球蛋白染色。能与人类横纹肌肉瘤发生反应。

免疫原

兔肌肉肌球蛋白。

應用

使用单克隆小鼠抗肌球蛋白（骨骼/快速）作为一抗，以1：90000的稀释度，通过蛋白质印迹对来自具有过去损伤的运动员的血清样品中的肌球蛋白（快）水平进行测定。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
免疫组织化学（1篇论文）

外觀

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Yanlin Wang et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 40(6), 1255-1265 (2019-03-21)
Myotonic dystrophy type 1 (DM1) is caused by CTG nucleotide repeat expansions in the 3'-untranslated region (3'-UTR) of the dystrophia myotonica protein kinase (DMPK) gene. The expanded CTG repeats encode toxic CUG RNAs that cause disease, largely through RNA gain-of-function.
Alan P Tenney et al.
Cell reports, 29(2), 437-452 (2019-10-10)
The somatotopic motor-neuron projections onto their cognate target muscles are essential for coordinated movement, but how that occurs for facial motor circuits, which have critical roles in respiratory and interactive behaviors, is poorly understood. We report extensive molecular heterogeneity in
Shirin Pourteymour et al.
Physiological reports, 3(8), doi:10-doi:10 (2015-08-13)
Perilipins (PLINs) coat the surface of lipid droplets and are important for the regulation of lipid turnover. Knowledge about the physiological role of the individual PLINs in skeletal muscle is limited although lipid metabolism is very important for muscle contraction.
Danielle Buck et al.
The Journal of general physiology, 143(2), 215-230 (2014-01-29)
Titin is a molecular spring that determines the passive stiffness of muscle cells. Changes in titin's stiffness occur in various myopathies, but whether these are a cause or an effect of the disease is unknown. We studied a novel mouse
David W Hammers et al.
EMBO molecular medicine, 9(4), 531-544 (2017-03-09)
Growth and differentiation factor (GDF) 11 is a member of the transforming growth factor β superfamily recently identified as a potential therapeutic for age-related cardiac and skeletal muscle decrements, despite high homology to myostatin (Mstn), a potent negative regulator of
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