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T-050

Supelco

Temazepam glucuronide lithium salt solution

100 μg/mL in methanol (as free carboxylate), ampule of 1 mL, certified reference material, Cerilliant®

同義詞:

Temazepam Glucuronide Solution

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About This Item

經驗公式（希爾表示法）:
C22H20ClLiN2O8
分子量：:
482.80
EC號碼:
200-659-6
MDL號碼:
MFCD29918103
分類程式碼代碼:
41116107
NACRES:
NA.24
暫時無法取得訂價和供貨情況

等級

certified reference material

品質等級

300

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland)

濃度

100 μg/mL in methanol (as free carboxylate)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

形式

single component solution

儲存溫度

−20°C

SMILES 字串

[Li+].CN1C(=O)C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C([O-])=O)N=C(c3ccccc3)c4cc(Cl)ccc14

InChI

1S/C22H21ClN2O8.Li/c1-25-13-8-7-11(23)9-12(13)14(10-5-3-2-4-6-10)24-19(20(25)29)33-22-17(28)15(26)16(27)18(32-22)21(30)31;/h2-9,15-19,22,26-28H,1H3,(H,30,31);/q;+1/p-1/t15-,16-,17+,18-,19?,22-;/m0./s1

InChI 密鑰

RQHXRNLYSZXQKI-NMJPLRNWSA-M

相關類別

一般說明

The major urinary and blood metabolite of temazepam, an intermediate-acting 3-hydroxy benzodiazepine prescribed for the short-term treatment of sleeplessness in patients with difficulties remaining asleep. This new Certified Reference Standard is suitable for a variety of LCMS and GCMS applications, including forensic and forensic toxicology analysis, urine drug testing, and hydrolysis controls.

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

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G W Kunsman et al.
Journal of chromatography, 568(2), 427-436 (1991-08-23)
A rapid and sensitive method for extracting temazepam from human serum and urine is presented. Free temazepam is extracted from plasma and urine samples using n-butyl chloride with nitrazepam as the internal standard. Temazepam glucuronide is analyzed as free temazepam
Commentary on: Dou C, Bournique J, Zinda M, Gnezda M, Nally A, Salamone S. Comparison of rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E. coli beta-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer.
Carol L O'Neal et al.
Journal of forensic sciences, 47(2), 427-428 (2002-03-23)

條款

UHPLC/MS for Drug Detection in Urine

Optimize β-glucuronidase hydrolysis for glucuronide metabolite analysis considering factors like time, temperature, pH, and enzyme concentration.

使用UHPLC/MS（TOF）检测不同酶水解条件处理的尿液中药物和代谢物

为了使用β-葡糖醛酸酶优化水解，必须对每种待分析的葡糖苷酸代谢物进行某些因素的评估，例如孵育时间、温度、水解pH、酶源和酶浓度。

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