跳轉至內容
Merck
全部照片(2)

重要文件

檢視所有文件

860646P

Avanti

C18 Ceramide (d17:1/18:0)

Avanti Research™ - A Croda Brand 860646P, powder

同義詞:

N-stearoyl-D-erythro-sphingosine (C17 base)

登入查看組織和合約定價
全部照片(2)

About This Item

經驗公式（希爾表示法）:
C35H69NO3
CAS號碼:
123065-42-9
分子量：:
551.93
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

形狀

powder

包裝

pkg of 1 × 10 mg (860646P-10mg)

製造商／商標名

Avanti Research™ - A Croda Brand 860646P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

InChI 密鑰

KGEXFGDEDXQZLQ-QKSCFGQVSA-N

一般說明

Ceramide is a bioactive sphingolipid. C18 Ceramide (d17:1/18:0) is synthesized by the N-acylation of sphingosine.[1] This reaction is catalyzed by ceramide synthase 1 (CerS1).[2] C18 Ceramide is highly expressed in brain tissues.[1]

應用

C18 Ceramide (d17:1/18:0) has been used as an internal standard in mass spectrometer and ultra high performance Liquid Chromatography for quantitative measurement of ceramides in muscle.[3]

生化／生理作用

C18 Ceramide has an ability to induce cell death.[4] Defects in the generation or accumulation of C18 Ceramide has been associated with the development of human head and neck squamous cell carcinomas (HNSCC).[2]

包裝

5 mL Amber Glass Screw Cap Vial (860646P-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如果您需要協助，請聯絡 客戶支援

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C18-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis
Karahatay S, et al.
Cancer Letters, 256(1), 101-111 (2007)
Koichi Ishida et al.
The Journal of investigative dermatology (2020-02-06)
Little is known about the pathophysiological linkages between altered ceramide profiles in the stratum corneum (SC) of patients with atopic dermatitis and their impaired skin barrier and water-holding functions. We studied those characteristics following topical treatment with a designed synthetic
Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats
Wang Y, et al.
The Journal of Nutritional Biochemistry, 64(5), 182-197 (2019)
Diverse functions of ceramide in cancer cell death and proliferation
Advances in Cancer Research, 117, 37-58 (2013)
The structure of D-erythro-C18 ceramide at the air-water interface
Vaknin D and Kelley MS
Biophysical Journal, 79(5), 2616-2623 (2000)
查看所有相關論文

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務