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860533P

Avanti

C16 1-磷酸神经酰胺(d18:1/16:0)

Avanti Research™ - A Croda Brand 860533P, powder

同義詞:

N-十六烷酰-神经酰胺-1-磷酸盐（胺盐）

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About This Item

經驗公式（希爾表示法）:
C34H71N2O6P
CAS號碼:
1246303-22-9
分子量：:
634.91
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

形狀

powder

包裝

pkg of 1 × 1 mg (860533P-1mg)

製造商／商標名

Avanti Research™ - A Croda Brand 860533P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

InChI

1S/C34H68NO6P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(36)32(31-41-42(38,39)40)35-34(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h27,29,32-33,36H,3-26,28,30-31H2,1-2H3,(H,35,37)(H2,38,39,40);1H3/b29-27+;/t32-,33+;/m0./s1

InChI 密鑰

RCRVTEZMCBPWGN-YWBCJBABSA-N

一般說明

C16神经酰胺-1-磷酸酯（d18:1/16:0）或N-棕榈酰神经酰胺-1-磷酸酯是天然的长链神经酰胺。[1]

應用

C16神经酰胺-1-磷酸酯（d18:1/16:0）或N-棕榈酰神经酰胺-1-磷酸酯已用于脂质制备中，以处理内皮集落形成细胞（ECFC）进行核形态分析。[1]它还被用作细胞迁移测定中的生物活性脂质，以研究其对多能基质细胞（MSC）和人脐静脉内皮细胞（HUVEC）的作用。[2]

包裝

5 mL棕色玻璃螺旋盖小瓶（860533P-1mg）

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

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分析證明 (COA)

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Chihwa Kim et al.
Stem cells (Dayton, Ohio), 31(3), 500-510 (2012-11-30)
Ceramide-1-phosphate (C1P) is a bioactive lipid that, in contrast to ceramide, is an antiapoptotic molecule released from cells that are damaged and "leaky." As reported recently, C1P promotes migration of hematopoietic cells. In this article, we tested the hypothesis that
Hebe Agustina Mena et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(10), e219-e232 (2019-08-23)
Ceramide 1-phosphate (C1P) is a bioactive sphingolipid highly augmented in damaged tissues. Because of its abilities to stimulate migration of murine bone marrow-derived progenitor cells, it has been suggested that C1P might be involved in tissue regeneration. In the present
V T Hinkovska-Galcheva et al.
The Journal of biological chemistry, 273(50), 33203-33209 (1998-12-05)
Ceramide, a product of agonist-stimulated sphingomyelinase activation, is known to be generated during the phagocytosis of antibody-coated erythrocytes by polymorphonuclear leukocytes. Agonist-stimulated formation of ceramide-1-phosphate is now shown to occur in 32PO4-labeled neutrophils. Ceramide-1-phosphate is formed by a calcium-dependent ceramide
Antonio Gómez-Muñoz et al.
Journal of lipid research, 45(1), 99-105 (2003-10-03)
It was reported previously that ceramide-1-phosphate (Cer-1-P) is mitogenic for fibroblasts (Gómez-Muñoz, A., P. A. Duffy, A. Martin, L. O'Brien, H-S. Byun, R. Bittman, and D. N. Brindley. 1995. Mol. Pharmacol. 47: 883-889; Gómez-Muñoz, A., L. M. Frago, L. Alvarez
A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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