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841118P

Avanti

Egg Trans PE

L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), powder

同義詞:

L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)

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About This Item

CAS號碼:
383907-63-9
MDL號碼:
MFCD00672608
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 25 mg (841118P-25mg)

製造商／商標名

Avanti Research™ - A Croda Brand 841118P

脂質類型

phosphoglycerides

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

InChI 密鑰

FHQVHHIBKUMWTI-OTMQOFQLSA-N

一般說明

Phosphatidylethanolamine (PE) is a phospholipid found in all living organisms.[1] The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group.[2] The egg yolk contains high levels of unsaturated PE which accounts to 83.10%.[3]

應用

Egg Trans PE is suitable for use:
  • in the preparation of zwitterionic liposome for binding assay[4]
  • as a component in optimized theranostic nanoemulsion (NE) formulations[5]
  • in the preparation of large unilamellar vesicles (LUVs) for detecting the leakage of intraliposomal carboxyfluorescein caused by anthraquinones[6]

生化／生理作用

Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation.[1] Egg yolk PE has high radical scavenging activity owing to antioxidant potential.[3]

包裝

5 mL Clear Glass Sealed Ampule (841118P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

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分析證明 (COA)

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Niravkumar R Patel et al.
Cancer biology & therapy, 19(7), 554-564 (2018-05-09)
Ovarian cancer ranks fifth in cancer related deaths for women in USA. The high mortality rate associated with ovarian cancer is due to diagnosis at later stages of disease and the high recurrence rate of 60-80%. Recurrent ovarian cancers are
The
The Membranes of Cells, 22(3) (2016)
Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein
Harrington JM, et al.
Journal of biological and chemical chronicles, 284(20), 13505-13512 (2009)
Egg Yolk Phosphatidylethanolamine: Extraction Optimization, Antioxidative Activity, and Molecular Structure Profiling
Sun N, et al.
Journal of Food Science, 84(5), 1002-1011 (2019)
In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers
Patel NR, et al.
Cancer Biochemistry Biophysics, 19(7), 554-564 (2018)
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