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重要文件

841118C

Avanti

Egg Trans PE

L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), chloroform

同義詞:

L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (841118C-25mg)

製造商/商標名

Avanti Research - A Croda Brand 841118C

濃度

10 mg/mL (841118C-25mg)

脂質類型

phosphoglycerides

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

InChI 密鑰

FHQVHHIBKUMWTI-OTMQOFQLSA-N

一般說明

Phosphatidylethanolamine (PE) is a phospholipid found in all living organism.[1] The egg yolk contains high levels of unsaturated PE which accounts to 83.10%.[2] The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group.[3]

應用

Egg Trans PE is suitable for use:
  • in the incubation of platelets for phospholipid enrichment and quantification by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)[4]
  • in the synthesis of isoketals-phosphatidylethanolamine (IsoK-PE)[5]
  • in the preparation of phospholipid vesicles for factor X activation studies[6]

生化/生理作用

Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation.[1] Egg yolk PE has high radical scavenging activity owing to antioxidant potential.[2]

包裝

5 mL Clear Glass Sealed Ampule (841118C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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The
The Membranes of Cells, 22(3) (2016)
Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake
Bloem E, et al.
Journal of biological and chemical chronicles, 288(41), 29670-29679 (2013)
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells
Sullivan CB, et al.
Journal of Lipid Research, 51(5), 999-1009 (2010)
C Blake Sullivan et al.
Journal of lipid research, 51(5), 999-1009 (2009-12-08)
Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are gamma-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions including cardiovascular disease. IsoKs can induce ion channel
Analytical characterization of the role of phospholipids in platelet adhesion and secretion
Koseoglu S, et al.
Analytical Chemistry, 87(1), 413-421 (2014)

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