810211C

C12-NBD Ceramide

Avanti Research^™ - A Croda Brand 810211C

• 同義詞: N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine
• 經驗公式（希爾表示法）: C₃₆H₆₁N₅O₆
• CAS號碼: 202850-01-9
• 分子量：: 659.90
• MDL號碼: MFCD02259239
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 化驗: >99% (TLC)
• 形狀: liquid
• 包裝: pkg of 1 × 1 mL (810211C-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 810211C
• 濃度: 1 mg/mL (810211C-1mg)
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO
• InChI: 1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1
• InChI 密鑰: SNOJCYCOPNIGIK-ULETYAGTSA-N

描述

應用

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases[1]
• in in vitro ceramidase activity assay[2]
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)[3]

生化／生理作用

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.[4]

包裝

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H302,H315,H319,H331,H336,H351,H361d,H372
• 防範說明: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 標靶器官: Central nervous system
• 水污染物質分類（WGK）: WGK 3