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790304P

Avanti

Coag Reagent I

Avanti Research - A Croda Brand 790304P, powder

同義詞:

Coag Reagent, Coagulation Reagent I, contains DOPE:DOPS:DOPC (5:3:2 w/w)

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About This Item

分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

形狀

powder

包裝

pkg of 2 × 100 mg (790304P-200mg)
pkg of 1 × 25 mg (790304P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 790304P

應用

microbiology

脂質類型

phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

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一般說明

Coag Reagent I comprises 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in the ratio 5:3:2 w/w. They are present predominantly in the synaptic vesicle membrane.[1] DOPC has choline group and DOPE comprises ethanolamine moiety. At neutral pH, DOPE and DOPC exist as a zwitterion whereas DOPS takes up a negative charge and has a serine group.[2]

應用

Coag Reagent I has been used in the preparation of small unilamellar vesicles (SUVs) for α-synuclein binding studies.[3][1] It may be used in the preparation of bilayers for reconstituting ryanodine receptor type 2 (RyR2) for single-channel recording studies.[4] It may be used for glass supported lipid bilayers preparation.[2]

生化/生理作用

Coag Reagent I mixed lipid is useful in the preparation of supported lipid bilayers and platelet membranes for coagulation studies.[2] It is used in the small unilamellar vesicles (SUVs) generation for α-synuclein and squalamine binding studies.[1]

包裝

5 mL Clear Glass Sealed Ampule (790304P-200mg)
5 mL Clear Glass Sealed Ampule (790304P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available


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EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2
Klipp RC, et al.
Heart Rhythm : the Official Journal of the Heart Rhythm Society, 15(4), 578-586 (2018)
A natural product inhibits the initiation of alpha-synuclein aggregation and suppresses its toxicity
Perni M, et al.
Proceedings of the National Academy of Sciences of the USA, 114(6), E1009-E1017 (2017)
Three-Dimensional Heterogeneous Structure Formation on a Supported Lipid Bilayer Disclosed by Single-Particle Tracking
Zhong Y & Wang G
Langmuir, 34(39), 11857-11865 (2018)
A M van den Besselaar et al.
Clinical chemistry, 43(7), 1215-1222 (1997-07-01)
To contribute to the development of a reference reagent for monitoring heparin therapy, a lyophilized partial thromboplastin time (PTT) reagent was prepared from synthetic dioleoylphosphatidylcholine, dioleoylphosphatidylserine, and dioleoylphosphatidylethanolamine, with colloidal silica as activator. The reagent, coded 91/558, was contained in
Nuclear magnetic resonance observation of ?-synuclein membrane interaction by monitoring the acetylation reactivity of its lysine side chains
Lee JH, et al.
Biochemistry, 55(35), 4949-4959 (2016)

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