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重要文件

W308307

Sigma-Aldrich

柠檬酸三乙酯

≥99%, FCC, FG

同義詞:

柠檬酸乙酯

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About This Item

線性公式:
HOC(COOC2H5)(CH2COOC2H5)2
CAS號碼:
分子量::
276.28
FEMA號碼:
3083
Beilstein:
1801199
EC號碼:
歐洲委員會號碼:
11762
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
9.512
NACRES:
NA.21
agency:
meets purity specifications of JECFA
暫時無法取得訂價和供貨情況

生物源

synthetic

品質等級

等級

FG
Halal
Kosher

agency

meets purity specifications of JECFA

法律遵循

EU Regulation 1334/2008 & 872/2012
FCC
FDA 21 CFR 117
FDA 21 CFR 175.300
FDA 21 CFR 175.320
FDA 21 CFR 181.27
FDA 21 CFR 184.1911

蒸汽密度

9.7 (vs air)

蒸汽壓力

1 mmHg ( 107 °C)

化驗

≥99%

折射率

n20/D 1.442 (lit.)

bp

235 °C/150 mmHg (lit.)

密度

1.14 g/mL at 25 °C (lit.)

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

感官的

odorless

SMILES 字串

CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC

InChI

1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3

InChI 密鑰

DOOTYTYQINUNNV-UHFFFAOYSA-N

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一般說明

柠檬酸三乙酯可用作食品工业中的塑化剂和螯合剂。[1][2]

應用


  • 经批准可用于化妆品的无表面活性剂的短链醇/柠檬酸三乙酯/水微乳液及其在熊果苷经皮渗透中的潜在应用:本研究探讨了使用柠檬酸三乙酯制备无表面活性剂微乳液,探索了其增强熊果苷经皮渗透的潜力。结果表明,皮肤中的递送有显著改善,突出了柠檬酸三乙酯用于美容品和药物的潜力 (Zhang et al., 2024)。

  • 理解热熔挤出过程中对聚乙烯醇基体系的可加工性至关重要的热、流变和机械参数的相互作用: 该研究深入探讨了柠檬酸三乙酯作为增塑剂在聚乙烯醇基体系中的作用,这对热熔挤出工艺的优化至关重要。这些发现强调了精确的热力和机械控制在制药应用中的重要性(Hess et al., 2024)。

  • 添加剂对聚羟基脂肪酸酯(PHA)生物降解的影响。: 研究人员评估了作为添加剂用于改善海洋环境中聚羟基烷酸酯生物降解的柠檬酸三乙酯。该研究展示了其通过加速降解增进环境可持续性的功效(Read et al., 2024)。

  • 原位成型PLGA植入物:转向毒性较小的溶剂。: 该论文研究了柠檬酸三乙酯作为PLGA植入物中毒性较低的溶剂替代品的用途,证明了其在保持植入物疗效的同时降低毒性的潜力,有利于药物应用(Ramos et al., 2024)。

  • 低分子量酯对聚乳酸纤维熔融纺丝和结构的影响: 该论文探讨了柠檬酸三乙酯对聚乳酸纤维性质的影响,强调了其在增强纤维结构和工业应用加工性能方面的作用(Gzyra-Jagieła et al., 2024

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

311.0 °F - closed cup

閃點(°C)

155 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Food Additives, 682-682 (1999)
Dictionary of Food ingredients, 144-144 (2013)
H M Fadda et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(3), 493-497 (2010-08-31)
Glass transition temperature (T(g)) measurements of polymers are conventionally conducted in the dry state with little attention to the environment they are designed to work in. Our aim was to develop the novel use of dynamic mechanical analysis (DMA) to
Shital M Maru et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 44(4), 471-478 (2011-09-20)
The influence of antiretroviral drugs and plasticizers on the rheological and thermal characteristics of ethyl cellulose formulations intended for hot melt extrusion has been investigated. Antiretroviral drugs used were zidovudine and lamivudine, whilst plasticizers included triethylcitrate (TEC) and polyethylene glycol
T Quinten et al.
AAPS PharmSciTech, 13(4), 1197-1211 (2012-09-12)
Sustained-release matrix tablets based on Eudragit RL and RS were manufactured by injection moulding. The influence of process temperature; matrix composition; drug load, plasticizer level; and salt form of metoprolol: tartrate (MPT), fumarate (MPF) and succinate (MPS) on ease of

Questions

1–10 of 11 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Do you supply a USP grade of material? I am not looking for an reference standard. We will use this in the product formula.

    1 answer
    1. Triethyl citrate is not supplied as USP grade material. This product meets purity specifications of JECFA (The Joint FAO/WHO Expert Committee on Food Additives). All available documentation for regulatory purposes can be found under the "Documentation" section of the product's webpage.

      Helpful?

  4. How do I reconstitute Product W308307, Triethyl citrate?

    1 answer
    1. You can reconstitute Triethyl citrate in water at a concentration of 65 g/l. (27500 product pink database)

      Helpful?

  5. What is the meaning of FCC?

    1 answer
    1. FCC refers to Food Chemical Codex. To products of this category testings done are based on the Government Food Grade products guidelines.(F&F group).

      Helpful?

  6. What grade is Product W308307, Triethyl citrate, and how do I get the Certificates on this product?

    1 answer
    1. The product W308307 is classified under the following grades: Food grade (FG), FCC, HALAL, Kosher and NI grade. The Certificates are available from our website or contact [email protected] or call 1-800-325-5832.

      Helpful?

  7. Is there any alcohol present in Product W308307, Triethyl citrate?

    1 answer
    1. The final product will have alcohol present. It will be less than 0.05 wt %. (ipi)

      Helpful?

  8. What amount is there in the SAMPLE size of Product W308307, Triethyl citrate?

    1 answer
    1. Sample package size contains 10 grams.

      Helpful?

  9. How do I convert the solid unit package to liquid volume for Product W308307, Triethyl citrate?

    1 answer
    1. If you divide the package size by the density of Triethyl citrate (1.14 g/ml), you can get the volume amount in that package. Example: 1000 gm/1.14 g/ml which is 877.19 ml.

      Helpful?

  10. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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1–10 of 11 Questions  

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