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Merck
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D68401

Sigma-Aldrich

2,4-二氯-1-硝基苯

97%

同義詞:

1,3-二氯-4-硝基苯, 不对称硝基间二氯苯

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About This Item

線性公式:
Cl2C6H3NO2
CAS號碼:
分子量::
192.00
Beilstein:
1451655
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

化驗

97%

形狀

solid

bp

258 °C (lit.)

mp

29-32 °C (lit.)

SMILES 字串

[O-][N+](=O)c1ccc(Cl)cc1Cl

InChI

1S/C6H3Cl2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H

InChI 密鑰

QUIMTLZDMCNYGY-UHFFFAOYSA-N

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Muta. 2 - Skin Sens. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Toxicology letters, 177(1), 74-82 (2008-02-19)
The development of non-animal methods for skin sensitization testing is an urgent challenge. Some of the most promising in vitro approaches are based on the analysis of phenotypical and functional modifications induced by sensitizers in dendritic cell models. In this
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Toxicology in vitro : an international journal published in association with BIBRA, 21(4), 723-733 (2007-02-24)
Covalent modification of skin proteins by electrophiles is a key event in the induction of skin sensitisation but not skin irritation although the exact nature of the binding mechanisms has not been determined empirically for the vast majority of sensitisers.
R M Bolton et al.
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Ammonium 4-chloro-7-sulfobenzofurazan (Sbf-Cl) is a water-soluble fluorescent reagent which is highly specific for thiol groups. We describe here a simple and sensitive fluorescence assay which is highly specific for subunit 3 of the rat glutathione S-transferases. Specific activities of isoenzymes
Teresa J Matos et al.
Journal of dermatological science, 39(2), 113-123 (2005-05-18)
The intracellular mechanisms involved in the activation of DCs during sensitization in allergic contact dermatitis (ACD) are not known. Here, we investigated the effect of a strong sensitizer, 2,4-dinitrofluorobenzene (DNFB) on the activity of MAPKs in a dendritic cell (DC)

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