900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 同義詞: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• 經驗公式（希爾表示法）: C₁₂H₁₄BrFO₂SSi
• CAS號碼: 2088828-99-1
• 分子量：: 349.29
• MDL號碼: MFCD31625432
• 分類程式碼代碼: 12352200
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder or crystals
• 存貨情形: available only in USA
• 儲存溫度: −20°C
• SMILES 字串: O=S(C(C(C#C[Si](C)(C)C)=C1)=CC=C1CBr)(F)=O
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)7-6-11-8-10(9-13)4-5-12(11)17(14,15)16/h4-5,8H,9H2,1-3H3
• InChI 密鑰: WFOCWDDRVBJLGX-UHFFFAOYSA-N

描述

應用

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他說明

• 1.Technology Spotlight: Trifunctional Probe Building Blocks
• 2.Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全資訊

• 象形圖: GHS02
• 訊號詞: Danger
• 危險聲明: H242
• 防範說明: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危險分類: Self-react. C
• 儲存類別代碼: 5.2 - Organic peroxides and self-reacting hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable