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化驗
≥85%
形狀
powder
分子量
344.24
反應適用性
reagent type: cross-linking reagent
儲存條件
desiccated
溶解度
DMSO or DMF: soluble
運輸包裝
ambient
儲存溫度
2-8°C
SMILES 字串
O=C(C(O)C(O)C(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O
InChI
1S/C12H12N2O10/c15-5-1-2-6(16)13(5)23-11(21)9(19)10(20)12(22)24-14-7(17)3-4-8(14)18/h9-10,19-20H,1-4H2
InChI 密鑰
NXVYSVARUKNFNF-UHFFFAOYSA-N
一般說明
DST is a homobifunctional crosslinker that contains amine-reactive N-hydroxysuccinimide (NHS) ester groups and is periodate cleavable. DST is commonly used for conjugating radiolabeled ligands to cell surface receptors. DST must first be dissolved in an organic solvent, such as DMSO or DMF, then added to the aqueous reaction mixture. DST is lipophilic, membrane-permeable and does not possess a charged group, which makes it useful for intracellular and intramembrane protein conjugation.
特點和優勢
- Reactive groups: NHS ester (both ends)
- Reactive towards: amino groups (primary amines)
- Soluble in DMSO or DMF at a concentration of ~10 mM (3 mg/mL)
- Cleavable by sodium meta-periodate (Part No. 20504)
- Ideal for applications in which crosslink cleavability is desired without disturbing protein disulfide bonds
注意
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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