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739979

Sigma-Aldrich

Resomer® RG 858 S,聚(D,L-丙交酯--乙交酯)

ester terminated, lactide:glycolide 85:15, Mw 190,000-240,000

同義詞:

PLGA

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About This Item

線性公式:
[C3H4O2]x[C2H2O2]y
CAS號碼:
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23
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品質等級

形狀

amorphous

饋電比

lactide:glycolide 85:15

分子量

Mw 190,000-240,000

降解時間

<9 months

黏度

1.3-1.7 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

儲存溫度

2-8°C

SMILES 字串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

一般說明

RESOMER®聚合物是生物可吸收的脂肪族聚酯,它由一系列不同比例的丙交酯和乙交酯单体、PLA立体化学和端基官能化组成。这些丙交酯和乙交酯的生物可降解均聚物和共聚物具有多种特性,其范围从降解时间长的刚性硬质半晶体材料到降解速率更快、更软的无定形材料。[1]

應用

Electrospun Resomer® X 206 S与来自甘蔗渣的纤维素混合,可用作组织工程中的支架。
控制释放

特點和優勢

生物活性剂的控制释放、缝合线和生物可吸收性可植入装置。

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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RESOMER??Biodegradeable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Mader K
Material Matters, 6(3), 62-62 (2011)
Maria Kirzhner et al.
Ophthalmology, 120(6), 1300-1304 (2013-02-13)
To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies. Retrospective, interventional cohort study. All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital. Review and
Igor Jeroukhimov et al.
Journal of the American College of Surgeons, 218(1), 102-107 (2013-11-12)
Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures
Teresa Musumeci et al.
International journal of pharmaceutics, 440(2), 135-140 (2012-10-20)
Melatonin, a neurohormone secreted by the pineal gland, is able to modulate intraocular pressure (IOP). The aim of this study was to generate nanoparticle (NPs) sustained release formulations that allow to extend the pre-corneal residence time of melatonin, thus prolonging
Kyle E Broaders et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5497-5502 (2009-03-27)
Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated dextran, a biocompatible material that can be formed into microparticles with degradation rates that

文章

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

合成脂肪族聚酯在臨床使用的可吸收生物材料中佔主導地位。

Ali 脂肪族聚酯(包括聚乳酸和聚乙二醇)是可生物降解的聚合物,廣泛應用於醫療領域。

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