跳轉至內容
Merck
全部照片(3)

重要文件

68255

Sigma-Aldrich

4-甲基-2-氧戊酸

≥98.0% (T)

同義詞:

2-羰基异己酸, 4-甲基-2-氧基戊酸, α-酮异己酸, 酮亮氨酸

登入查看組織和合約定價


About This Item

線性公式:
(CH3)2CHCH2COCOOH
CAS號碼:
分子量::
130.14
Beilstein:
1701823
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
暫時無法取得訂價和供貨情況

化驗

≥98.0% (T)

折射率

n20/D 1.431

bp

82-83 °C/11 mmHg (lit.)

mp

8-10 °C

密度

1.055 g/mL at 20 °C (lit.)

官能基

carboxylic acid
ketone

儲存溫度

2-8°C

SMILES 字串

CC(C)CC(=O)C(O)=O

InChI

1S/C6H10O3/c1-4(2)3-5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)

InChI 密鑰

BKAJNAXTPSGJCU-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

4-Methyl-2-oxovaleric acid, also known as α-ketoisocaproic acid (KIC), is a metabolite of leucine. [1]It is commonly used as a building block in the synthesis of leucine and its derivatives, and it plays a role in amination reactions and asymmetric synthesis.[2] Additionally, KIC serves as an intermediate in the formation of Strecker aldehydes.[3]

應用

  • 在人脑酮体代谢中的作用:4-甲基-2-氧戊酸参与创伤性脑损伤患者脑微透析液中酮体代谢的时间模式,说明其在大脑生化通路中的重要作用(Eiden et al., 2019)。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Lisa S Chow et al.
American journal of physiology. Endocrinology and metabolism, 291(4), E729-E736 (2006-05-18)
Despite being an anabolic hormone in skeletal muscle, insulin's anticatabolic mechanism in humans remains controversial, with contradictory reports showing either stimulation of protein synthesis (PS) or inhibition of protein breakdown (PB) by insulin. Earlier measurements of muscle PS and PB
The First Highly Enantioselective Homogeneously Catalyzed Asymmetric Reductive Amination:? Synthesis of ?-N-Benzylamino Acids
Kadyrov et al.
The Journal of Organic Chemistry, 68, 4067-4070 (2003)
Intermediate role of ?-keto acids in the formation of Strecker aldehydes
Hidalgo et al.
Basic Food Chemistry, 141, 1140-1146 (2013)
Direct Analysis of Leucine and Its Metabolites ??Hydroxy-?-methylbutyric Acid, ??Ketoisocaproic Acid, and ??HydroxyisocaproicAcid in Human Breast Milk by Liquid Chromatography?MassSpectrometry
Ehling et al.
Journal of Agricultural and Food Chemistry, 63, 7567-7573 (2015)
Eiji Yoshihara et al.
Nature communications, 1, 127-127 (2010-12-02)
Type 2 diabetes mellitus (T2DM) is characterized by defects in both insulin sensitivity and glucose-stimulated insulin secretion (GSIS) and is often accompanied by obesity. In this study, we show that disruption of thioredoxin binding protein-2 (TBP-2, also called Txnip) in

Questions

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務