663190

5-甲基吲哚-2-羧酸乙酯

97%

• 同義詞: 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• 經驗公式（希爾表示法）: C₁₂H₁₃NO₂
• CAS號碼: 16382-15-3
• 分子量：: 203.24
• MDL號碼: MFCD00022703
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24884618
• NACRES: NA.22

屬性

• 化驗: 97%
• 形狀: solid
• mp: 160-164 °C
• 官能基: ester
• SMILES 字串: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• InChI 密鑰: KMVFKXFOPNKHEM-UHFFFAOYSA-N

描述

一般說明

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.[1]

應用

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)