661082

2,4-二氟嘧啶

97%

• 經驗公式（希爾表示法）: C₄H₂F₂N₂
• CAS號碼: 2802-61-1
• 分子量：: 116.07
• MDL號碼: MFCD04972830
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24884500
• NACRES: NA.22

屬性

• 化驗: 97%
• 折射率: n20/D 1.432
• bp: 118-120 °C
• 密度: 1.359 g/mL at 25 °C
• 官能基: fluoro
• SMILES 字串: Fc1ccnc(F)n1
• InChI: 1S/C4H2F2N2/c5-3-1-2-7-4(6)8-3/h1-2H
• InChI 密鑰: JZSYSXZDIQUOGP-UHFFFAOYSA-N

描述

應用

2,4-Difluoropyrimidine can be used as a starting material to synthesize:

• 3-Pyrimidin-4-yl-oxazolidin-2-one derivatives as mutant isocitrate dehydrogenase (IDH₁) inhibitors.[1]
• N,N′-(1,4-phenylenebis(methylene))bis(2-fluoropyrimidin-4-amine) as chemokine receptor type 4 antagonists.[2]

安全資訊

• 象形圖: GHS02,GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H226,H302,H315,H318,H335
• 防範說明: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 106.0 °F - closed cup
• 閃點（°C）: 41.1 °C - closed cup
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter