全部照片(1)
About This Item
線性公式:
F2C6H3MgBr
CAS號碼:
分子量::
217.29
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
暫時無法取得訂價和供貨情況
推薦產品
反應適用性
reaction type: Grignard Reaction
品質等級
濃度
0.5 M in THF
bp
65 °C
密度
0.965 g/mL at 25 °C
官能基
fluoro
儲存溫度
2-8°C
SMILES 字串
Fc1ccc([Mg]Br)cc1F
InChI
1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1
InChI 密鑰
WZHAVYGMKGPNFN-UHFFFAOYSA-M
應用
3,4-Difluorophenylmagnesium bromide can be used:
- To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.[1]
- In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.[2]
- In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.[3]
- In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.[4]
法律資訊
Rieke® Metals, Inc. 产品 ®Rieke Metals, Inc. 的注册商标
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
標靶器官
Respiratory system
安全危害
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
1.0 °F - closed cup
閃點(°C)
-17.2 °C - closed cup
Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation
Lukas RJ, et al.
Journal of Medicinal Chemistry, 53(12), 4731-4748 (2010)
Synthesis and monoamine transporter binding properties of 3α-(substituted phenyl) nortropane-2β-carboxylic acid methyl esters. Norepinephrine transporter selective compounds
Carroll FI, et al.
Journal of medicinal chemistry, 48(11), 3852-3857 (2005)
Discovery of novel diarylketoxime derivatives as selective and orally active melanin-concentrating hormone 1 receptor antagonists
Suzuki T, et al.
Bioorganic & medicinal chemistry letters, 19(18), 5339-5345 (2009)
2?Amino?3, 4, 5?Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors.
Chuang H Y, et al.
ChemMedChem, 6(3), 450-456 (2011)
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務